2014
DOI: 10.1001/jamaophthalmol.2014.160
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Iris Stromal Cyst Management With Absolute Alcohol–Induced Sclerosis in 16 Patients

Abstract: The management of symptomatic iris stromal cyst is challenging using methods of aspiration with or without adjunctive cryotherapy, intracameral cautery, or photocoagulation. Failed cases often require surgical resection, with risks for epithelial downgrowth, glaucoma, blindness, and loss of the eye.OBJECTIVE To study the safety and efficacy of the management of iris stromal cysts with aspiration and alcohol irrigation to induce cyst sclerosis. DESIGN, SETTING, AND PARTICIPANTSInterventional case series at a te… Show more

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Cited by 36 publications
(26 citation statements)
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“…However, some concern exists about releasing potentially toxic cyst contents into the eye with this technique [7]. Needle cyst aspiration is more invasive but permits the draining of cyst contents, and may be combined with adjunctive therapy such as cryotherapy or instillation of sclerosing agents to decrease the likelihood of cyst recurrence [4]. In some cases, iris pigment epithelial cysts may cause large anterior synechiae, and surgical synechiolysis may be desired.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…However, some concern exists about releasing potentially toxic cyst contents into the eye with this technique [7]. Needle cyst aspiration is more invasive but permits the draining of cyst contents, and may be combined with adjunctive therapy such as cryotherapy or instillation of sclerosing agents to decrease the likelihood of cyst recurrence [4]. In some cases, iris pigment epithelial cysts may cause large anterior synechiae, and surgical synechiolysis may be desired.…”
Section: Discussionmentioning
confidence: 99%
“…Current management options include needle aspiration with or without adjunctive cryotherapy [4, 5], laser photocoagulation or cystotomy [3, 6], and en bloc surgical resection [5]. We present a surgical technique to collapse an iris pigment epithelial cyst using microsurgical instruments introduced via paracentesis.…”
Section: Introductionmentioning
confidence: 99%
“…However, the results showed that it often requires 2 sclerosis procedures to obtain complete cyst collapse. Failure of this technique will need surgical intervention eventually [7].…”
Section: Discussionmentioning
confidence: 99%
“…Iris cysts are classified into primary and secondary types with several subtypes of each [1,2,3,4,5,6,7,8,9]. Primary iris cysts are further subclassified into cysts of the iris stroma and cysts of the iris pigment epithelium.…”
Section: Introductionmentioning
confidence: 99%
“…Primary iris cysts are further subclassified into cysts of the iris stroma and cysts of the iris pigment epithelium. Iris stromal cysts demonstrate more aggressive features, particularly in young infants, with large sizes, endothelial adhesion, angle closure, glaucoma, and severe photophobia due to microruptures, often requiring interventional therapy [8]. By contrast, iris pigment epithelial (IPE) cysts are classified into central, midzonal, peripheral, free-floating, and dislodged, with a more quiescent stationary course, and they rarely require intervention [5,7].…”
Section: Introductionmentioning
confidence: 99%