Ionizing and non-ionizing electromagnetic radiation in modern medicine

Sowa, Paweł; Rutkowska-Talipska, Joanna; Sulkowska, Urszula; Rutkowski, Krzysztof; Rutkowski, Ryszard

doi:10.1016/j.poamed.2012.07.001

Cited by 17 publications

(6 citation statements)

References 22 publications

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“…Günümüzde radyasyon bazlı teknolojilerin nispeten güvenli ve verimli olması ve radyasyon kaynaklarının daha sıkı denetimine rağmen, modern yaşamın birçok rutin faaliyetleri sıra-sında iyonize radyasyona maruz kalınmaktadır (15). İyonize radyasyon ya hedef molekülleri etkileyerek doğrudan ya da hücre disfonksiyonu ve ölümüne neden olan OH • , HO 2 • ve O 2…”

Section: Discussionunclassified

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Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments

Çelik¹,

Koyuncu²,

Karakılçık³

et al. 2016

Bezmialem Science

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ÖZAmaç: Bu araştırma radyasyonlu ortamlarda çalışan erkeklerde iyonize (İR) ve non-iyonize (NİR) radyasyonun total antioksidan seviye ve oksidatif stres üzerindeki etkilerini araştırmak amacı ile yapıldı. Yöntemler: Kontrol ve Radyasyona maruz kalan erkeklerin serumlarında total oksidan seviye (TOS), malondialdehit (MDA) ve protein karbonil (PC) değerleri ölçüldü. Ayrıca total antioksidan seviye (TAS) ve oksidatif stres değerleri belirlendi; oksidatif stresi belirlemek için oksidatif stres indeksi (OSİ) hesaplandı. Veriler istatistiksel SPSS 20,0 (Chicago, ABD) programı ile analiz edildi. Bulgular: İyonize grubunda serum PC, MDA, TOS ve OSİ dü-zeyleri kontrol grubuna göre anlamlı düzeyde yüksek bulunurken TAS düzeyleri düşük bulundu (sırasıyla; p<0,001, p=0,003, p<0,001, p<0,001 ve p=0,002). NİR grubunda ise serum PC, TOS ve OSİ düzeyleri kontrol grubuna göre anlamlı düzeyde yüksek bulunurken TAS ve MDA düzeyleri arasında anlamlı bir fark bulunamadı (sırasıyla; p<0,001, p=0,021, p=0,010, p>0,05 ve p>0,05). Sonuç: Bu verilere göre, İR'de daha fazla olmak üzere İR ve NİR gruplarında oksidan/antioksidan dengenin oksidanlar lehine bozulduğu görüldü. Bu oksidatif stres etkisi ile DNA, lipitler ve proteinler gibi birçok hücresel makromolekülde hasar oluşabilir. Anahtar Kelimeler: İyonize radyasyon, non-iyonize radyasyon, total oksidan seviye, malondialdehit, protein karbonil, total antioksidan seviye, oksidatif stres indeksi ABSTRACTObjective: This study was conducted to investigate the effects of ionizing radiation (IR) and non-ionizing radiation (NIR) on oxidative stress and the total antioxidant status (TAS) in men working in radiation environments. Methods:The serum values of total oxidant status (TOS), malondialdehyde (MDA), and protein carbonyl (PC) in men exposed to radiation and a control group were determined. In addition, the values of the total antioxidant status (TAS) were measured in serum, and the oxidative stress index (OSI) was calculated to determine the oxidative stress. Data were analyzed by SPSS 20.0 (Chicago, IL, USA). Results: While the serum values of PC, MDA, TOS, and OSI were significantly higher in the IR group than in the control group, those of TAS were significantly lower (p<0. 001, p=0.003, p<0.001, p<0.001, and p= 0.002, respectively). The serum values of PC, TOS, and OSI were significantly higher in the NIR group than in the control group (p<0.001, p=0.021, and p=0.010, respectively). In contrast, there were no significant differences in the values of TAS and MDA (p>0.05 and p>0.05, respectively) in the same groups. Conclusion: Based on these results, we determined that it had been damaged the balance between oxidants and antioxidant status in the IR and NIR groups. This effect of oxidative stress may cause a lot of damage to cellular macromolecules including lipids, proteins, and DNA.

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Section: Discussionunclassified

“…Televizyon ve radyo vericileri, fotokopi makineleri, cep telefonu baz istasyonları, mikrodalga fırınlar, bilgisayar monitörleri ve kablosuz bağlantı cihazları (WiFi) gibi cihazlar ise NİR yaymaktadır (2).…”

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Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments

Çelik¹,

Koyuncu²,

Karakılçık³

et al. 2016

Bezmialem Science

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“…The OH• radical causes fragmentation and aggregation of proteins. In addition, ROS disrupts the physicochemical properties of the cell membrane by causing lipid peroxidation (18,19). Although there are several mechanisms that explain the biological effects of ionizing radiation in various tissues, molecular mechanisms cannot yet be explained (20).…”

Section: Discussionmentioning

confidence: 99%

The effect of computed tomography on oxidative stress level and some antioxidant parameters

et al. 2020

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Background X-rays are defined as ionizing radiation and hydrolyze the water, causing free radical formation. Oxidative stress is the damage that occurs in cells due to the lack of antioxidants, which detoxifies them, with the increased production of free radicals that occur during normal cellular metabolism. Purpose To examine the acute effects of computed tomography (CT), i.e. ionizing radiation, on oxidative stress and antioxidant defense mechanisms. Material and Methods The study included a total of 53 patients that were selected among the patients that underwent non-contrast full-body CT. Malondialdehyde (MDA) and reduced glutathione (GSH) levels and superoxide dismutase (SOD) and catalase (CAT) activities were investigated in blood samples taken from patients. Results The post-scan levels of MDA increased significantly while the post-scan levels of GSH, SOD, and CAT decreased significantly compared to their pre-scan levels. Conclusion CT, which is a widely used X-ray imaging technique and has numerous known side effects, was found to increase the levels of MDA, which is an indicator of oxidative stress, and to decrease the levels of some antioxidants including GSH, SOD, and CAT.

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“…The non-ionizing radiation used in MR apparatuses has significantly lower energy than ionizing radiation and has been verified to have no harmful effects on the human body. Moreover, imaging using a magnetic field directly stimulates hydrogen nuclei present in each tissue allowing the acquisition of high-resolution images unlike the ionizing radiation that exploits interactions with tissues [6,7]. In addition, compared with CT, MRI is more effective in observing areas surrounded by air or bones and is widely used in clinical practice for a precise diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Simulation and Experimental Studies of Optimization of σ-Value for Block Matching and 3D Filtering Algorithm in Magnetic Resonance Images

Park,

Kang,

Kim

et al. 2023

Applied Sciences

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In this study, we optimized the σ-values of a block matching and 3D filtering (BM3D) algorithm to reduce noise in magnetic resonance images. Brain T2-weighted images (T2WIs) were obtained using the BrainWeb simulation program and Rician noise with intensities of 0.05, 0.10, and 0.15. The BM3D algorithm was applied to the optimized BM3D algorithm and compared with conventional noise reduction algorithms using Gaussian, median, and Wiener filters. The clinical feasibility was assessed using real brain T2WIs from the Alzheimer’s Disease Neuroimaging Initiative. Quantitative evaluation was performed using the contrast-to-noise ratio, coefficient of variation, structural similarity index measurement, and root mean square error. The simulation results showed optimal image characteristics and similarity at a σ-value of 0.12, demonstrating superior noise reduction performance. The optimized BM3D algorithm showed the greatest improvement in the clinical study. In conclusion, applying the optimized BM3D algorithm with a σ-value of 0.12 achieved efficient noise reduction.

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Ionizing and non-ionizing electromagnetic radiation in modern medicine

Cited by 17 publications

References 22 publications

Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments

Effects of Ionizing and Non-Ionizing Radiation on Oxidative Stress and the Total Antioxidant Status in Humans Working in Radiation Environments

The effect of computed tomography on oxidative stress level and some antioxidant parameters

Simulation and Experimental Studies of Optimization of σ-Value for Block Matching and 3D Filtering Algorithm in Magnetic Resonance Images

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