Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2012.03.010 View full text
Leslie Boudesocque, Pedro Lameiras, Nassima Amarouche, Matthieu Giraud, Francesca Quattrini, John Mc Garrity, Jean-Marc Nuzillard, Jean-Hugues Renault

Abstract: This article presents the scope and optimization strategies employed in ion-exchange centrifugal partition chromatography (IXCPC). Both the weak and the strong modes were used to separate the constituents of a model mixture of dipeptides. Thus, the combined use of the quaternary biphasic solvent system, methyl-tert-butylether/acetonitrile/n-butanol/water (2:1:2:5, v/v) in the descending mode, of the lipophilic di(2-ethylhexyl)phosphoric acid (DEHPA) cation-exchanger, and of two displacers: calcium chloride and…

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