Iodoform and silver-coated abutments preventing bacterial leakage through the implant-abutment interfaces: In vitro analysis using molecular-based method

Nascimento, Cássio do; Fernandes, Flávio Henrique Carriço Nogueira; Teixeira, Wendel; Pedrazzi, Vinícius

doi:10.1016/j.archoralbio.2019.06.009

Cited by 5 publications

(12 citation statements)

References 28 publications

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“…Therefore it was stated, that they may serve as drug carriers which improve tissue adaptation by decreasing the bacterial leakage during early period of implant adaptation, providing better implant- tissue interface seal and in turn- better resistance to infections in the subsequent period of implant functioning when loaded with final prosthetic superstructure. 22 , 44 , 45 …”

Section: Discussionmentioning

confidence: 99%

“…A leakage test showed a significant reduction of clinically isolated multispecies oral bacteria in the test group than in the control (no sealant) showing that drug delivery at the implant-abutment, abutment-tissue interface is an important factor that may decrease the percentage of implant failure due to infection or the development of a defective tissue seal. 44 In another study, De Avila et al described LbL coating assembly as a sufficient method for surface optimization that reduced the adhesion of P. gingivalis on the titanium surface. Their method also increased the surface roughness and changed its topography.…”

Section: Discussionmentioning

confidence: 99%

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Dental Implant Healing Screws as Temporary Oral Drug Delivery Systems for Decrease of Infections in the Area of the Head and Neck

Pokrowiecki¹,

Szałaj²,

Fudala³

et al. 2022

IJN

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Background Periimplantitis is continuously one of major threats for the uneventful functioning of dental implants. Current approaches of drug delivery systems are being more commonly implemented into oral- and maxillofacial biomaterials in order to decrease the risk of implant failure due to bacterial infection. Silver nanoparticles and their compounds have been proven in eradicating oral bacteria responsible for peri-implant infections. Nevertheless, their evaluation as coating for implant abutments has not been extensively evaluated so far. This article describes a novel coating consisting of zinc oxide (ZnO) and silver (Ag) nanoparticles (NPs). This coating was used to modify healing abutments that could be used as drug delivery systems in oral implantology. Materials and Method Nanoparticles with a ZnO + 0.1% Ag composition were produced by microwave solvothermal synthesis and then incorporated into the surface of titanium healing abutments by high-power ultrasonic deposition. Surface morphology, roughness, wettability were evaluated. Ability of biofilm formation inhibition was tested against S. mutans, S. oralis, S. aureus and E. coli . Results ZnO+0.1%Ag NPs were sufficiently deposed on the surface of the abutments creating nanostructured coating which increased surface roughness and decreased wettability. Modified abutments significantly decreased bacterial biofilm formation. Bacteria present in SEM studies were unlikely to settle and replicate on the experimental abutments as their cells were rounded, insufficiently spread on the surface and covered with released NPs. Conclusion Experimental nanostructured abutments were easily manufactured by high-power ultrasonic deposition and provided significant antibacterial properties. Such biomaterials could be used as temporary drug delivery abutments for prevention and treatment of intra- and extraoral peri-implant infections in the area of the head and neck.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Dental Implant Healing Screws as Temporary Oral Drug Delivery Systems for Decrease of Infections in the Area of the Head and Neck

Pokrowiecki¹,

Szałaj²,

Fudala³

et al. 2022

IJN

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“…For this reason, 4 weeks before performing the regenerative surgical therapy, it was necessary to perform a removal of the previous prosthetic artifact and at the same time, iodoform paste was inserted together with a new cap screw. 11 It is important to underline that the removal of the crown allows from a clinical point of view a better access to the pocket and to the surface to be decontaminated.…”

Section: Discussionmentioning

confidence: 99%

“…After 1 week from decontamination, the crown on implant 2.1 is removed, the cap screw is inserted with application of iodoform paste 11 and then a maryland bridge has been placed (►Fig. 4).…”

Section: Methodsmentioning

confidence: 99%

Electrolytic Cleaning and Regenerative Therapy of Peri-implantitis in the Esthetic Area: A Case Report

et al. 2022

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Implantology represents the gold standard in oral rehabilitation. Unfortunately, a new pathology begins to show itself to clinicians that no longer affects only and solely the supporting tissues of the tooth but also dental implants and peri-implantitis. In this study, we present a case report regarding a tissue regeneration maneuver involving dental implants. The clinical and radiographic results are encouraging, regarding the use of these techniques on implant surfaces. Surely, the advent of new biomaterials and surgical techniques will make this practice safe and predictable.

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“…A prata tem se apresentado como um material promissor como agente antimicrobiano e seu uso associado ao Ti poderia resultar em benefícios de maneira acessível para paciente e profissional (Zheng et al, 2012;Godoy-Gallardo et al, 2015;Cal et al, 2017;Kheur et al, 2017;Smanio, 2017;Vilarrasa et al, 2018;Nascimento et al, 2019;Salaie et al, 2020;Sobolev et al, 2019).…”

Section: Discussionunclassified

Avaliação da citotoxicidade de filmes antimicrobianos nanoestruturados em discos de titânio: análise em cultura de fibroblastos

Mahfoud¹

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in memoriam), pelos ensinamentos durante as monitorias nas clínicas semanais. Aos pacientes da FOUSP que foram essenciais para a realização desse estudo e de tantos outros, colaborando diariamente para o desenvolvimento da pesquisa em Odontologia. Aos alunos da FOUSP que confiaram a mim a tarefa de auxiliá-los durante sua trajetória na clínica integrada e ao mesmo tempo me possibilitaram aprender tanto sobre a arte de ensinar. Ao meu querido orientador Prof. Dr. Rodney Garcia Rocha, que desde a graduação foi uma inspiração para mim com seu jeito didático e amável de lecionar, agradeço por todo o apoio e incentivo em todo o percurso. Ao Prof. Dr. Marcelo Munhóes Romano por estar sempre disponível para me ajudar, por acreditar na minha capacidade de conclusão desse estudo e por me incentivar diante das dificuldades. Sempre serei grata por tudo que me ensinou e por ser uma inspiração na sala de aula e na clínica para mim, o mundo precisa de mais profissionais dedicados assim. Ao Prof. Dr. Carlos Alberto Adde por ter sido um professor tão querido quando estava cursando a disciplina de Clínica Integrada em minha graduação que me despertou o interesse pela área acadêmica e apoiou meu ingresso no Mestrado. Palavras-chave: Periimplantite. Fibroblastos. Filmes nanoestruturados. Prata.

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Iodoform and silver-coated abutments preventing bacterial leakage through the implant-abutment interfaces: In vitro analysis using molecular-based method

Cited by 5 publications

References 28 publications

Dental Implant Healing Screws as Temporary Oral Drug Delivery Systems for Decrease of Infections in the Area of the Head and Neck

Dental Implant Healing Screws as Temporary Oral Drug Delivery Systems for Decrease of Infections in the Area of the Head and Neck

Electrolytic Cleaning and Regenerative Therapy of Peri-implantitis in the Esthetic Area: A Case Report

Avaliação da citotoxicidade de filmes antimicrobianos nanoestruturados em discos de titânio: análise em cultura de fibroblastos

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