Iodine intake from supplements and diet during pregnancy and child cognitive and motor development: the INMA Mother and Child Cohort Study

Abstract

We found an association between low maternal urinary iodine and lower cognitive scores in childhood, although only when corrected for creatinine, adding to the evidence that iodine deficiency may have potential harmful effects on neurodevelopment. Iodine supplementation does not appear to improve child's neurodevelopment at 4-5 years.

Haurdunaldian amak izandako bizi-ohiturak, ingurumen-esposizioak, osasun-sistemaren ekimenak eta haurraren garapen neuropsikologikoa. INMA (Haurtzaroa eta Ingurumena-Infancia y Medio Ambiente) proiektuan argitaratutako lanen errebisioa

“…Aztertu diren 25 artikuluetako sei bizi-ohiturekin [9][10][11][12][13][14], hamaika ingurumenarekin [15][16][17][18][19][20][21][22][23][24][25] eta zortzi osasun-sistemak emandako jarraibideekin [26][27][28][29][30][31][32][33] (p = 0,03), arrain txuriaren (p = 0,10) eta Bayley eskala mentalaren artean. Eskala psikomotorearekin aurkitu zen asoziazioa, positiboa eta ahula izan zen.…”

“…Bestalde, emakumeek iodoa osagarri bitartez >150 µg/ eguneko dosian hartzea haurrek 14 hilabeterekin azpieskala mentalean puntuazio altuagoak izatearekin lotu zen (BSID) [27]. Gernuko iodo kontzentrazioei dagokienez, haurdunaldian zehar amak <100 µg/l izatea 4 urtetan haurren garapen baxuago batekin asoziatu zen (MSCA) [28]. Emaitza hauek bat datoz egun dagoen ebidentziarekin [57].…”

A multivariate discrete failure time model for the analysis of infant motor development

“…23 The AHEI-P quantifies diet quality based on the consumption of both nutrients (eg, calcium) and individual foods (eg, vegetables). The original AHEI-P did not include a category for nuts/soy/beans Age of crawling (months) 8 (7,9) Age of walking (months) 12 ( because these were not previously recommended for pregnant mothers. However, because current recommendations no longer include these restrictions, we incorporated the nuts/soy/beans category into our assessment per the original AHEI.…”

“…Predictors of motor milestone achievement include infant birth weight and gestational age, breastfeeding, and gestational diabetes . Previous studies have also assessed nutrient intake during pregnancy and motor development . However, these studies have focused on specific components of maternal diet (eg, fish intake) rather than diet quality as a whole.…”

“…7 Previous studies have also assessed nutrient intake during pregnancy and motor development. 8,9 However, these studies have focused on specific components of maternal diet (eg, fish intake) rather than diet quality as a whole. To our knowledge, no prior studies have examined overall diet quality in pregnancy and offspring motor development, even though there is strong evidence that maternal diet is an important predictor of fetal development, 10 which may, in turn, affect motor milestone achievement.…”