Iodine-123 metaiodobenzylguanidine myocardial imaging in haemodialysed patients asymptomatic for coronary artery disease

Abstract

I-mIBG scintigraphy can detect very early stages of cardiac sympathetic dysfunction. Low values of HMR and high values of WOR suggest an impaired cardiac adrenergic system in patients without any relevant symptoms of heart failure. Low values of HRV may confirm cardiac autonomic neuropathy.

Ultrasound validation of Trendelenburg positioning to increase internal jugular vein cross-sectional area in chronic dialysis patients

“…All of the patients were positioned with their neck in extension and head rotated left at [20][21][22][23][24][25][26][27][28][29][30] . Patients were studied in State 0, table flat (no tilt), with the patients in the supine position, and State T, in which the operating table was tilted 15 to a TP.…”

“…2,[23][24][25] Anemia, left ventricular hypertrophy, diastolic dysfunction and vascular dysfunction are all the characteristic manifestations in dialysis patients. An increasing number of older dialysis patients with diabetes mellitus and autonomic neuropathy caused by uremic poisoning of the baroreceptors [25][26][27] may stimulates morbidity of autonomic disorder in dialysis patients. Stimulation of the sympathetic nervous system seems to be the mechanism that is likely to cause cardiovascular complications, including sudden cardiac death, in chronically dialyzed patients.…”

“…10 Therefore, excessive left rotation should be avoided to minimize the risk of unintentional CA puncture during right IJV cannulation. In the present study, each patient's head was positioned with the head rotated left at [20][21][22][23][24][25][26][27][28][29][30] . According to our review of the literature, the effects of TP on the overlap between the CA and the IJV have not yet been evaluated.…”

Relationship of haemodialysis therapy duration and cardiac adrenergic system function assessed by iodine-123 metaiodobenzylguanidine imaging in haemodialysed nondiabetic patients

“…The semiquantitative assessment comprised calculation of the heart-to-mediastinum ratio (HMR) and the myocardial washout rate (WOR) according to the European Association of Nuclear Medicine standard proposed [29] and previously described methods [17]. To calculate HMR, two regions of interest (ROIs) in the anterior planar image were determined (Fig.…”

“…Cardiovascular causes account for at least 40% of deaths in ESRD patients, of which 20% are sudden [12]. Cardiovascular mortality and morbidity, as well as cardiac SNS impairment in ESRD patients have been well understood [6,7,[13][14][15][16][17][18]. Different radiopharmaceuticals have been used to evaluate the cardiac adrenergic system.…”