Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.12.015 View full text
Hong Gao, Paul G. Stevenson, Fabrice Gritti, Georges Guiochon

Abstract: Elution peaks were generated by summing up a mathematical function and a previously recorded experimental noise. The first three statistical moments of these peaks were calculated using several data processing methods. The results obtained were analyzed. From this analysis, a method is developed for the calculation with a satisfying accuracy of the third moments of these combined signals. The method is applicable to real chromatographic peaks and makes it possible to determine accurate estimates of their third…

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