2020
DOI: 10.1007/s42770-020-00326-w
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Vulvovaginal candidiasis is a serious health problem affecting numerous women around the world. Its treatment is based on antifungals which may not provide an effective cure because of the resistance presented by its etiological pathogens Candida spp. Candida albicans is the most prevalent species related to vulvovaginal candidiasis. Here, we evaluated the in vivo antifungal potential of thiosemicarbazide and thiosemicarbazide encapsulated within chitosan nanoparticles in a murine model of vulvovaginal candidi… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1

Citation Types

0
3
0

Year Published

2021
2021
2022
2022

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(3 citation statements)
references
References 50 publications
0
3
0
Order By: Relevance
“…Thiosemicarbazide is a compound with an antifungal effect, but its biological effect is reduced due to in vivo degradation. The CNP-associated thiosemicarbazide obtained a noticeable reduction in the fungal burden after seven days of treatment, suggesting a synergistic effect [287]. CNPs alone did not affect the fungal burden.…”
Section: Particles and Carriersmentioning
confidence: 88%
See 2 more Smart Citations
“…Thiosemicarbazide is a compound with an antifungal effect, but its biological effect is reduced due to in vivo degradation. The CNP-associated thiosemicarbazide obtained a noticeable reduction in the fungal burden after seven days of treatment, suggesting a synergistic effect [287]. CNPs alone did not affect the fungal burden.…”
Section: Particles and Carriersmentioning
confidence: 88%
“…Clotrimazole Decreased antifungal activity in vitro but improved safety profile for CNP-associated clotrimazole [285] Callophycin A Synergetic and improved antifungal effect both in vitro and in vivo by Callophycin A in CNPs [286] Thiosemicarbazide CNP-associated thiosemicarbazide obtained a prominent reduction of fungal burden in vivo [287] Miconazole CNPs containing a seven-fold lower miconazole concentration than conventional miconazole cream obtained equal therapeutic effect [288] Miconazole and farnesol…”
Section: Candidiasismentioning
confidence: 99%
See 1 more Smart Citation