Investigation of biological activity of Lamii albi flos extracts

Paduch, Roman; Wójciak–Kosior, Magdalena; Matysik, G.

doi:10.1016/j.jep.2006.09.004

Cited by 40 publications

(41 citation statements)

References 19 publications

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“…This provides the base knowledge to understand the beneficial properties of a particular food product and further stimulate consumers' interest in it. In the particular case of L. album L., the phenolic compounds have been closely associated with the antioxidant properties of the plant (Matkowski & Piotrowska, 2006;Valyova, Dimitrova, Ganeva, Mihova Kapchina-Toteva, & Petkova Yordanova, 2011), as well as to its remaining health benefits (Paduch et al, 2008;Paduch, Wójciak-Kosior, & Matysik, 2007).…”

Section: Introductionmentioning

confidence: 99%

“…In this way, several L. album L. phenolic compounds have already been detected, which include the flavonoids quercetin, quercetin-3-Oglucoside, rutin, isoquercitrin, kaempferol-3-O-glucoside and tiliroside, the phenolic acids protocatechuic, chlorogenic, vanillic and caffeic and the phenylpropanoid glycoside ester derivatives lamalboside, acteoside and isoacteoside (Budzianowski & Skrzypczak, 1995;Paduch et al, 2007;Yalcin & Kaya, 2006). However despite that information, a detailed knowledge of the L. album L. phenolic constituents, as well as their content in the plant, is still missing.…”

Section: Introductionmentioning

confidence: 99%

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Phenolic constituents of Lamium album: Focus on isoscutellarein derivatives

Pereira

Domingues

Silva

et al. 2012

Food Research International

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Lamium album L. is an edible plant which is consumed raw or cooked, in particular in the Mediterranean and surrounding areas. It is also consumed as tea infusions and as a main component of food supplements, because of its pharmacological effects. Despite being consumed by humans for centuries, the chemical composition of L. album L. is far from being understood. In this study, a purified ethanolic extract (PEEL) was prepared and further analyzed by high performance liquid chromatography and electrospray mass spectrometry. Overall, verbascoside accounted for approximately half of the phenolic content of the extract, but this also contained other bioactive phenolic compounds herein detected for the first time in the genus, namely isoscutellarein derivatives. The latter included isoscutellarein-7-O-allosyl(1 →2)glucoside, its O-methyl derivative, three acetyl derivatives of isoscutellarein-Oallosyl glucoside and one acetylated form of O-methylisoscutellarein-7-O-allosyl(1 →2)glucoside. From those, the main isoscutellarein derivative was assigned to isoscutellarein-7-O-(6-O-acetyl-β-allosyl)(1→2)-β-glucoside, as confirmed by NMR. Altogether, isoscutellarein derivatives accounted for almost 30% of PEEL phenolics. Since verbascoside and isoscutellarein derivatives are main components of L. album L. ethanolic extract, their possible association to the health benefits of the plant is discussed.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Phenolic constituents of Lamium album: Focus on isoscutellarein derivatives

Pereira

Domingues

Silva

et al. 2012

Food Research International

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“…2003). For this reason, many studies were conducted on the phytochemical constituents of Lamium species and their biological activities (Savchenko et al 2001;Flamini et al 2005;Alipieva et al 2007;Ersöz et al 2007;Paduch et al 2007). In addition, they are traditionally consumed as food in some countries (Bremness 1995;Baytop 1999;Cui et al 2003).…”

Section: Introductionmentioning

confidence: 99%

Morphological, anatomical and cytological investigation on endemic Lamium moschatum var. rhodium

Baran

Özdemır

2011

Biologia

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In this study, the morphological and anatomical features of endemic Lamium moschatum Miller var. rhodium (Gand.) R. Mill (Lamiaceae) are described in detail. Lamium moschatum var. rhodium has an annual taproot. The stem is erect and clearly quadrangular. The leaves are broadly ovate to cordate-ovate or nearly suborbicular in shape. Inflorescense is verticillate cyme. The corolla is white and the tube is curved and bears an annulus inside, near the base. Cross-sections of the root, stem, petiole, leaf, calyx, corolla and generative organs were examined and the anatomical features of the taxon are discussed. Furthermore, glandular hairs distributed on the plant taxon are shown. In karyological research, chromosome numbers were determined as 2n = 18. The results are presented with photographs and tables.

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“…It was shown that methanol, ethyl acetate and heptane extracts of Lamii albi flos L. had no toxic effects on normal human skin fibroblasts (HSF) in the range of concentrations (25-225 μg/ml) and that heptane extracts of Lamii albi flos L significant stimulated human skin fibroblasts proliferation and those properties may be used in designing of new medicinal preparation (5,6). In a previous publication we demonstrated that methanol extracts obtain by Soxhlet extraction of in vivo cultivated plants of Lamium albim L. had high amount of total phenols and antioxidant capacity measured by DPPH-and ABTS-radical scavenging activities.…”

Section: Fig 2 Effect Of 24 H and 48 H Treatment With Different Combmentioning

confidence: 99%

“…It possesses a wide spectrum of therapeutic activities -antiinflammatory, astringent, antiseptic, antibiotic, antispasmodic, antioxidant and anti-proliferative, which is related to the variety of biologically active substances which could be found in that plant: flavonoids, iridoids, phenolic acids, polysaccharides, triterpenes, saponins, phytoecdysteroids, amines, essential oils, tannins and mucilage (5). On the other hand dried flowers of Lamium album L. possess antioxidant, antiproliferative, mucolytic and antispasmodic activity and different extracts of Lamii albi flos stimulate growth human skin fibroblasts in vitro (6,7). Prior to usage dried extracts were diluted in 1ml DMSO and sonicated with ultrasound for completed dissolving.…”

Section: Introductionmentioning

confidence: 99%