Investigating different type of ovary cancer cell line for NK cell in vitro co-culture cytotoxic assay

Pangjaya, Lady Feren; Khaerunnisa, Sanya; Mazfufah, Nuzli Fahdia; Budiman, Retno Lestari; Antarianto, Radiana Dhewayani

doi:10.1063/5.0049155

Cited by 1 publication

(3 citation statements)

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“…Several therapies have been practiced for several years to treat cancer, such as chemotherapy and radiotherapy which seemed to cause resistance in the tumor cells or treatment of it within 3 years, that is why a proficient alternate source to cure cancer with promising results is being employed in which the NK cells perform specific anticancer activity-called immunotherapy. 20,41,42…”

Section: Immunotherapeutic Role Of Nk Cells In Different Cancersmentioning

confidence: 99%

“…Such sort of malignancies can be eradicated from the woman's body through the administration of NK cells to directly kill the tumor cells without damaging normal cells. 20,42…”

Section: Nk Cells In Ovarian Carcinomamentioning

confidence: 99%

“…There are only 29% survival chances for a woman even despite advanced treatment due to its asymptomatic nature, it is undetectable at early stages until ascites or adverse metastatic condition is examined beyond the pelvis. Such sort of malignancies can be eradicated from the woman's body through the administration of NK cells to directly kill the tumor cells without damaging normal cells 20,42 …”

Section: Immunotherapeutic Role Of Nk Cells In Different Cancersmentioning

confidence: 99%

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Breaking down barriers: The potential of smarter CAR‐engineered NK cells against solid tumors

Khawar,

Gao,

Rafiq

et al. 2023

J of Cellular Biochemistry

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Natural killer (NK) cells are considered to be the foremost fighters of our innate immune system against foreign invaders and thus tend to promptly latch onto the virus‐infected and tumor/cancerous cells, killing them through phagocytosis. At present, the application of genetically engineered Chimeric antigen receptor (CAR) receptors ensures a guaranteed optimistic response with NK cells and would not allow the affected cells to dodge or escape unchecked. Hence the specificity and uniqueness of CAR‐NK cells over CAR‐T therapy make them a better immunotherapeutic choice to reduce the load of trafficking of numerous tumor cells near the healthy cell populations in a more intact way than offered by CAR‐T immunotherapy. Our review mainly focuses on the preclinical, clinical, and recent advances in clinical research trials and further strategies to achieve an augmented and efficient cure against solid tumors.

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Section: Immunotherapeutic Role Of Nk Cells In Different Cancersmentioning

confidence: 99%

“…Such sort of malignancies can be eradicated from the woman's body through the administration of NK cells to directly kill the tumor cells without damaging normal cells. 20,42…”

Section: Nk Cells In Ovarian Carcinomamentioning

confidence: 99%

Section: Immunotherapeutic Role Of Nk Cells In Different Cancersmentioning

confidence: 99%

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