This paper studies matrix-valued truncated Toeplitz operators, which are a vectorial generalisation of truncated Toeplitz operators. It is demonstrated that, although there exist matrix-valued truncated Toeplitz operators without a matrix symbol in $$L^p$$
L
p
for any $$p \in (2, \infty ]$$
p
∈
(
2
,
∞
]
, there is a wide class of matrix-valued truncated Toeplitz operators which possess a matrix symbol in $$L^p$$
L
p
for some $$p \in (2, \infty ]$$
p
∈
(
2
,
∞
]
. In the case when the matrix-valued truncated Toeplitz operator has a symbol in $$L^p$$
L
p
for some $$p \in (2, \infty ]$$
p
∈
(
2
,
∞
]
, an approach is developed which bypasses some of the technical difficulties which arise when dealing with problems concerning matrix-valued truncated Toeplitz operators with unbounded symbols. Using this new approach, two new notable results are obtained. The kernel of the matrix-valued truncated Toeplitz operator is expressed as an isometric image of an $$S^*$$
S
∗
-invariant subspace. Also, a Toeplitz operator is constructed which is equivalent after extension to the matrix-valued truncated Toeplitz operator. In a different yet overlapping vein, it is also shown that multidimensional analogues of the truncated Wiener–Hopf operators are unitarily equivalent to certain matrix-valued truncated Toeplitz operators.