2018
DOI: 10.18632/aging.101529
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Abstract: Despite the potential detrimental effects of systemic inflammation on muscle mass, which is mainly observed in patients with pathologic diseases, its role in muscle strength, especially in a healthy general population reflecting subclinical low-grade inflammation, is unclear. This is a nationally representative population-based, cross-sectional study from the Korea National Health and Nutrition Examination Survey, which enrolled 1,036 men aged ≥50 years and 1,080 postmenopausal women. After adjustment for conf… Show more

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Cited by 10 publications
(8 citation statements)
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References 40 publications
(50 reference statements)
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“…Focusing on hsCRP, men with high levels of the inflammatory marker had significantly lower HGS compared to men with medium levels of hsCRP and women with high hsCRP had a 19.21% lower HGS compared to women with low levels of hsCRP. Other studies have found similar results for CRP and HGS [30][31][32] for both genders and a big, population-based, cross-sectional study from Korea from 2018 found a significant correlation between CRP and HGS in men only [33].…”
Section: Discussionsupporting
confidence: 64%
“…Focusing on hsCRP, men with high levels of the inflammatory marker had significantly lower HGS compared to men with medium levels of hsCRP and women with high hsCRP had a 19.21% lower HGS compared to women with low levels of hsCRP. Other studies have found similar results for CRP and HGS [30][31][32] for both genders and a big, population-based, cross-sectional study from Korea from 2018 found a significant correlation between CRP and HGS in men only [33].…”
Section: Discussionsupporting
confidence: 64%
“… 32 In contrast, Kim et al reported that the inverse relationship between hs-CRP and HGS was only in older men, not in postmenopausal women. 33 However, Smith et al showed inverse associations between HGS and inflammatory markers in women only, not in men. 34 These discrepancies in the results may have existed for several reasons, including using different HGS indexes, differences in ethnicity, sex, and body size.…”
Section: Discussionmentioning
confidence: 98%
“…CRP may also serve as a possible biomarker for infection and pneumonia in geriatric patients ( 66 ). Furthermore, CRP has been associated with HOMA-IR and inversely related with grip strength ( 63 , 67 ). Indeed, HOMA-IR decreased ( p < 0.05) in the present study and strength-to-weight ratio increased as previously reported ( 15 ).…”
Section: Discussionmentioning
confidence: 99%