Intubation Studies of the Human Small Intestine

Abbott, W. Osler; Karr, Walter G.; Glenn, Paul M.; Warren, Richard

doi:10.1097/00000441-194010000-00016

Cited by 9 publications

(3 citation statements)

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“…In 1940, Abbott et al [ 15 ] developed DT, which alleviates intestinal obstruction by repeatedly flushing the intestinal lumen upon reaching the site of obstruction. Studies have demonstrated the safety and efficacy of DT [ 16 – 19 ].…”

Section: Introductionmentioning

confidence: 99%

Self-expanding metal stents versus decompression tubes as a bridge to surgery for patients with obstruction caused by colorectal cancer: a systematic review and meta-analysis

Ma,

Zhang,

Luo

et al. 2023

World J Emerg Surg

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Background Using self-expanding metal stents (SEMS) and decompression tubes (DT) as a bridge-to-surgery (BTS) treatment may avoid emergency operations for patients with colorectal cancer-caused obstructions. This study aimed to evaluate the efficacy and safety of the two approaches. Methods We systematically retrieved literature from January 1, 2000, to May 30, 2023, from the PubMed, Embase, Web of Science, SinoMed, Wanfang Data, Chinese National Knowledge Infrastructure, and Cochrane Central Register of Clinical Trials databases. Randomized controlled trials (RCTs) or cohort studies of SEMS versus DT as BTS in colorectal cancer obstruction were selected. Risks of bias were assessed for RCTs and cohort studies using the Cochrane Risk of Bias tool version 2 and Risk of Bias in Nonrandomized Studies of Interventions. Certainty of evidence was determined using the Graded Recommendation Assessment. Odds ratio (OR), mean difference (MD), and 95% confidence interval (95% CI) were used to analyze measurement data. Results We included eight RCTs and eighteen cohort studies involving 2,061 patients (SEMS, 1,044; DT, 1,017). Pooled RCT and cohort data indicated the SEMS group had a significantly higher clinical success rate than the DT group (OR = 1.99, 95% CI 1.04, 3.81, P = 0.04), but no significant difference regarding technical success (OR = 1.29, 95% CI 0.56, 2.96, P = 0.55). SEMS had a shorter postoperative length of hospital stays (MD = − 4.47, 95% CI − 6.26, − 2.69, P < 0.00001), a lower rates of operation-related abdominal pain (OR = 0.16, 95% CI 0.05, 0.50, P = 0.002), intraoperative bleeding (MD = − 37.67, 95% CI − 62.73, − 12.60, P = 0.003), stoma creation (OR = 0.41, 95% CI 0.23, 0.73, P = 0.002) and long-term tumor recurrence rate than DT (OR = 0.47, 95% CI 0.22, 0.99, P = 0.05). Conclusion SEMS and DT are both safe as BTS to avoid emergency surgery for patients with colorectal cancer obstruction. SEMS is preferable because of higher clinical success rates, lower rates of operation-related abdominal pain, intraoperative bleeding, stoma creation, and long-term tumor recurrence, as well as a shorter postoperative length of hospital stays. Trial registrationCRD42022365951.

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Section: Introductionmentioning

confidence: 99%

Self-expanding metal stents versus decompression tubes as a bridge to surgery for patients with obstruction caused by colorectal cancer: a systematic review and meta-analysis

Ma,

Zhang,

Luo

et al. 2023

World J Emerg Surg

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“…Experiments using dogs (London and Polowzowa [9]; Frey [6] ; Radvin et al [13]) ; guinea-pigs (Straub and Leo [15]) ; and human subjects (Abbott et al [1], Shay [14], Machella [10], and Borgström [4]) have shown unanimously that such a solution rapidly increases in volume parallel with a fall in concentration until the intestinal content is isotonic with tissue fluid.…”

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confidence: 99%

“…In experiments with isolated sections of the small intestine from dogs, Frey [6] found that a hypertonic sugar solution would draw more sodium chloride into the intestinal lumen than would a hypo tonic one and the author deduced that the primary purpose of this equalization was to make the solution isotonic; on this point the theory received the support of later investigators (Straub and Leo [15] ; Abbott et al [1] ; Groen [8] ; and Peters [12] maintaining that a hyper tonic glucose solution in the small intestine is diluted with a hypo tonic solution containing sodium, chloride, and bicarbonate.…”

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The Electrolyte and Protein Concentration in Hypertonic Glucose Solutions 15 Minutes after Intra-Intestinal Injection into Small Intestinal Sections of Varying Lengths

et al. 1962

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Experimental examination of hypertonic glucose solutions injected into small intestinal sections from live pigs and aspirated 15 minutes later showed the following: The volume of a hypertonic glucose solution increases parallel with increasing length of the section of the jejunum into which the solution is diffused. The amount of sodium and chloride seeping in with the water during the experimental 15-minute-periods is equal to the rise in volume and thus the amounts of sodium and chloride seeping in vary with the size of the area of the mucous membrane on which the 50 ml of a 50% glucose solution is diffused. Not only the amount but also the concentration of sodium and chloride in the aspirates increases considerably when the intestinal sections are prolonged from 100 to 200 cm. A further prolongation rather impedes the increase in concentration. The volume, i.e. the sodium and chloride content of the transuded fluid, is uniform in at least six successive experiments in which the same intestinal section is exposed. The valuation of results from the potassium analyses cannot be quite as clear- cut, probably because of a certain admixture of blood corpuscles. In repeated experiments the protein concentration rises in the fluid in the intestinal lumen and a pronounced oedema of the intestinal wall and the mesentery is noted.

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Gastroenterology

Jones¹

1941

Arch Intern Med (Chic)

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Intubation Studies of the Human Small Intestine

Cited by 9 publications

References 0 publications

Self-expanding metal stents versus decompression tubes as a bridge to surgery for patients with obstruction caused by colorectal cancer: a systematic review and meta-analysis

Self-expanding metal stents versus decompression tubes as a bridge to surgery for patients with obstruction caused by colorectal cancer: a systematic review and meta-analysis

The Electrolyte and Protein Concentration in Hypertonic Glucose Solutions 15 Minutes after Intra-Intestinal Injection into Small Intestinal Sections of Varying Lengths

Gastroenterology

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