Introduction of the flash‐lamp pulsed‐dye laser treatment of facial port‐wine stains in childhood: A case of health care technology assessment

Borgie, Corianne A. J. M. de; Bossuyt, Patrick M.; Horst, Chantal M.A.M. van der; Gemert, Martin J. C. van

doi:10.1002/lsm.1037

Cited by 9 publications

(7 citation statements)

References 60 publications

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“…These methods can lead to the development of side effects such as scars and permanent depigmentation or. it is difficult to treat PWS without scarring [9][10][11]. So, laser therapy with pulsed dye laser (PDL) with epidermal cooling is a common treatment due to the low incidence of side effects.…”

Section: Introductionmentioning

confidence: 99%

Comparing the therapeutic effect of pulsed dye laser and pulsed dye laser plus CO2 in port wine stain

Sheng¹,

Zhong²,

Zhang³

2022

pdia

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Introduction: One of the most common congenital vascular abnormalities in the dermal area of the skin is the port-wine stain (PWS). Aim: Researchers are trying to introduce more effective new methods of treatment of PWS. Material and methods: This clinical trial study was conducted on 60 patients in Huanggang Central Hospital during May 2020 to June 2021. Pulsed dye laser (PDL) only and PDL plus CO2 methods were used to treat PWS, the clearance scores of patients were assessed for both methods, and the side effects were examined. Results: The mean age of the patients was 26.87 ±9.67 years. The majority of the patients (80%) were female. Thirty-four (56.66%) patients had PWS in the malar area, 14 (23.33%) on their forehead, 5 (8.33%) on their chin, and 7 (11.7%) on neck. The efficacy of the treatment through clearance score shows that the quantitative mean of the clearance score of the patients in the PDL method was 2.71 ±0.54, and in the CO2 + PDL method it was 2.72 ±0.56 (p > 0.05). The qualitative comparison of clearance scores indicated that in the PDL method, 18 (30%) patients had acceptable clearance, 30 (50%) patients had good clearance, and 12 (20%) patients had excellent clearance. Also, for the PDL plus CO 2 method, 25 (41.766) patients had acceptable clearance, 23 (38.34%) patients had good clearance, and 12 (20%) patients had excellent clearance. Conclusions: For PWS patients under treatment with PDL plus CO 2 , the hyperpigmentation side effect was greater than in patients with underlying PDL only.

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Section: Introductionmentioning

confidence: 99%

Comparing the therapeutic effect of pulsed dye laser and pulsed dye laser plus CO2 in port wine stain

Sheng¹,

Zhong²,

Zhang³

2022

pdia

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“…Lasers have been used to treat PWS for over 30 years. 8 As demonstrated by its clinical efficacy, the pulsed dye laser (PDL) is the treatment of choice for PWS. 9 Shakespeare et al 10 evaluated the influence of laser treatment on quality of life (QoL) and found a significant improvement in mental health after treatment.…”

Section: Introductionmentioning

confidence: 99%

Willingness to Pay and Time Trade-off in Thai Patients with Port-Wine Stains

Jantarakolica¹,

Wanitphakdeedecha²,

Yan³

et al. 2022

CEOR

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Background Port-wine stains are congenital vascular abnormalities that impact children’s and parents’ quality of life (QoL). There are currently no established criteria for assessing the quality of life in PWS patients. Utility measures such as willingness-to-pay (WTP) and time trade-off (TTO) can be used to quantify disease burden, impact on QoL, and assess the cost-effectiveness of interventions. Methods This was a cross-sectional questionnaire-based survey study in Thailand from July 2021 to April 2022. The questionnaire included sociodemographic data and preference-based measurement, WTP and TTO. The primary outcome was a WTP and TTO for PWS laser treatment. The subsample analysis for the primary outcome was based on gender (male and female) and age (<5 years and ≥5 years). The household income was measured for time trade-off outcome. Results Out of 46 respondents, WTP for the base case at 40% improvement cost 6109.01 baht per visit. Patients were willing to spend their time 9.95 hours per visit for a clinical improvement of 40%. Female was willing to pay and spend more time than male, while those aged≥5 years were willing to pay and spend more time than those aged <5 years. High household income >100k per month willing to spend less time than lower income groups. Conclusion There were obvious correlations between WTP and TTO with clinical outcomes. Utility indicators such as WTP and TTO can be used to measure disease burden, impact on QoL, and assess the cost-effectiveness of interventions. WTP and TTO could provide a more personalized approach to improving QoL, considering each patient’s unique treatment plan and priority. This could help with patient uncertainty and long-term planning strategies to increase the QoL cost-effectively.

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“…Lasers have been used in the treatment of PWS for more than 30 years. 7 The pulsed dye laser (PDL) is the treatment of choice as exhibited by its clinical efficacy. 8 It utilizes the principle of selective photothermolysis to injure the ectatic dermal capillaries, thereby reducing the redness and flattening the lesion.…”

Section: Introductionmentioning

confidence: 99%

Quality of Life and Psychological Effects of Port-Wine Stain: A Review of Literature

Wanitphakdeedecha¹,

Ng²,

Yan³

et al. 2021

CCID

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Introduction Port-wine stain (PWS) is a congenital malformation that does not resolve spontaneously and can cause a physiological or psychological burden to the patients. At present, most of the studies done on PWS are focused on the treatment rather than the quality of life and psychological effects of the disease. Material and Methods A comprehensive literature search was done in MEDLINE using PubMed database, Embase ® , and Cochrane. All observational studies were included in this review. Results A total of 17 relevant articles with 2,135 PWS patients were included in this review. There were 36 measurement tools used to assess the quality of life and the psychological effects among PWS patients. The results showed that patients with facial PWS had a significant negative effect on their quality of life and had also suffered from psychological disabilities. The PWS lesion tends to worsen with age and may cause further adaptation problems towards the social environment, especially in children. Conclusion Early treatment, psychological assistance, and patient support are the key management in improving the quality of life of patients with PWS. Quality of life must be regularly assessed together with the improvement of treatment.

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Introduction of the flash‐lamp pulsed‐dye laser treatment of facial port‐wine stains in childhood: A case of health care technology assessment

Cited by 9 publications

References 60 publications

Comparing the therapeutic effect of pulsed dye laser and pulsed dye laser plus CO2 in port wine stain

Comparing the therapeutic effect of pulsed dye laser and pulsed dye laser plus CO2 in port wine stain

Willingness to Pay and Time Trade-off in Thai Patients with Port-Wine Stains

Quality of Life and Psychological Effects of Port-Wine Stain: A Review of Literature

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