Intravitreal Longevity of Three Perfluorocarbon Gases

The Use of Polymers in the Treatment of Retinal Detachment: Current Trends and Future Perspectives

“…[35] In the early 1970s, Norton used sulfur hexafluoride (SF 6 ) for pneumatic retinopexy and found the persistence of gas and its expansive features superior to air [27]. In 1980 Lincoff et al [28] proposed the use of perfluorocarbon gases (PFCGs), i.e., C 2 F 6 , C 3 F 8 , C 4 F 8 and C 5 F 12 ; their advantages over SF 6 include a lower requirement of intravitreal injected volumes due to increased expansion and longer persistence thanks to their low solubility [29]. Thus, the use of PFCGs may result in a lower rise in initial IOP than that evaluated with SF 6 (acute glaucoma) because of the smaller injected volume.…”

The Use of Polymers in the Treatment of Retinal Detachment: Current Trends and Future Perspectives

“…[35] In the early 1970s, Norton used sulfur hexafluoride (SF 6 ) for pneumatic retinopexy and found the persistence of gas and its expansive features superior to air [27]. In 1980 Lincoff et al [28] proposed the use of perfluorocarbon gases (PFCGs), i.e., C 2 F 6 , C 3 F 8 , C 4 F 8 and C 5 F 12 ; their advantages over SF 6 include a lower requirement of intravitreal injected volumes due to increased expansion and longer persistence thanks to their low solubility [29]. Thus, the use of PFCGs may result in a lower rise in initial IOP than that evaluated with SF 6 (acute glaucoma) because of the smaller injected volume.…”

Intra-orbital gas following sutureless small-gauge (23-gauge) vitrectomy masquerading as orbital cellulitis

“…1 Sir, IgG4-related orbital inflammation presenting as bilateral proptosis in a child IgG4-related orbital disease is an immune-mediated fibro-inflammatory disease with systemic associations 1,2 and predominantly affects middle-aged and elderly patients, 2 presentation of IgG4-related orbital disease in children is very rare. 3,4 Figure 3 CT scan image of the orbit demonstrating extra-scleral loculated spaces (marked with an open white arrow) with the same radio-density as the intra-ocular gas.…”

Randomized clinical trial of intraocular silicone vs. gas in the management of complicated retinal detachment and vitreous hemorrhage

“…With the advent of vitrectomy, it was thought the surgical removal of vitreal tractional bands and preretinal membranes would sufficiently release forces that prevented retinal reattachment [20]. Because vitrectomy did not completely fulfill this expectation, there has been a renewed interest in tamponading the retina internally with silicone oil [6,10,11,13,15,22] or long-lasting gases such as C3F 8 [2,3,18,19] or C4F s [27,28,37].…”

The Use of Polymers in the Treatment of Retinal Detachment: Current Trends and Future Perspectives

“…[35] In the early 1970s, Norton used sulfur hexafluoride (SF 6 ) for pneumatic retinopexy and found the persistence of gas and its expansive features superior to air [27]. In 1980 Lincoff et al [28] proposed the use of perfluorocarbon gases (PFCGs), i.e., C 2 F 6 , C 3 F 8 , C 4 F 8 and C 5 F 12 ; their advantages over SF 6 include a lower requirement of intravitreal injected volumes due to increased expansion and longer persistence thanks to their low solubility [29]. Thus, the use of PFCGs may result in a lower rise in initial IOP than that evaluated with SF 6 (acute glaucoma) because of the smaller injected volume.…”

Intra-orbital gas following sutureless small-gauge (23-gauge) vitrectomy masquerading as orbital cellulitis

“…1 Sir, IgG4-related orbital inflammation presenting as bilateral proptosis in a child IgG4-related orbital disease is an immune-mediated fibro-inflammatory disease with systemic associations 1,2 and predominantly affects middle-aged and elderly patients, 2 presentation of IgG4-related orbital disease in children is very rare. 3,4 Figure 3 CT scan image of the orbit demonstrating extra-scleral loculated spaces (marked with an open white arrow) with the same radio-density as the intra-ocular gas.…”

Randomized clinical trial of intraocular silicone vs. gas in the management of complicated retinal detachment and vitreous hemorrhage

“…With the advent of vitrectomy, it was thought the surgical removal of vitreal tractional bands and preretinal membranes would sufficiently release forces that prevented retinal reattachment [20]. Because vitrectomy did not completely fulfill this expectation, there has been a renewed interest in tamponading the retina internally with silicone oil [6,10,11,13,15,22] or long-lasting gases such as C3F 8 [2,3,18,19] or C4F s [27,28,37].…”

The Use of Polymers in the Treatment of Retinal Detachment: Current Trends and Future Perspectives

“…[35] In the early 1970s, Norton used sulfur hexafluoride (SF 6 ) for pneumatic retinopexy and found the persistence of gas and its expansive features superior to air [27]. In 1980 Lincoff et al [28] proposed the use of perfluorocarbon gases (PFCGs), i.e., C 2 F 6 , C 3 F 8 , C 4 F 8 and C 5 F 12 ; their advantages over SF 6 include a lower requirement of intravitreal injected volumes due to increased expansion and longer persistence thanks to their low solubility [29]. Thus, the use of PFCGs may result in a lower rise in initial IOP than that evaluated with SF 6 (acute glaucoma) because of the smaller injected volume.…”

Intra-orbital gas following sutureless small-gauge (23-gauge) vitrectomy masquerading as orbital cellulitis

“…1 Sir, IgG4-related orbital inflammation presenting as bilateral proptosis in a child IgG4-related orbital disease is an immune-mediated fibro-inflammatory disease with systemic associations 1,2 and predominantly affects middle-aged and elderly patients, 2 presentation of IgG4-related orbital disease in children is very rare. 3,4 Figure 3 CT scan image of the orbit demonstrating extra-scleral loculated spaces (marked with an open white arrow) with the same radio-density as the intra-ocular gas.…”

Randomized clinical trial of intraocular silicone vs. gas in the management of complicated retinal detachment and vitreous hemorrhage

“…With the advent of vitrectomy, it was thought the surgical removal of vitreal tractional bands and preretinal membranes would sufficiently release forces that prevented retinal reattachment [20]. Because vitrectomy did not completely fulfill this expectation, there has been a renewed interest in tamponading the retina internally with silicone oil [6,10,11,13,15,22] or long-lasting gases such as C3F 8 [2,3,18,19] or C4F s [27,28,37].…”