Intravenous Pentazocine and Methylphenidate Abuse During Pregna

Investigation of possible teratogenic effects in the offspring of mice exposed to methylphenidate during pregnancy

“…This malformation seemed isolated and was not associated with the profile of any syndrome. One case of polydactyly has already been reported in a human study (Debooy et al, 1993).…”

The Use of Central Nervous System Active Drugs During Pregnancy

“…A risk increase of preterm birth, low birth weight and small-for gestational age is seen in infants whose mothers abused amphetamine (review in [138]). Also abuse of methylphenidate resulted in a high rate of preterm birth and growth retardation [139]. …”

First Trimester In Utero Exposure to Methylphenidate

“…The twins had malformations compatible with foetal alcohol syndrome, and major malformations were recorded in two other infants. This study was confounded by the concurrent abuse of cigarettes, alcohol, other drugs and concurrent diseases, and therefore was excluded [12]. Lastly, four papers were identified from the reference lists.…”