Intern. Med. volume 35, issue 8, P663-667 1996 DOI: 10.2169/internalmedicine.35.663 View full text
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Masato MORIGUCHI, Takahiro SUZUKI, Mutsuto TATEISHI, Masako HARA, Sadao KASHIWAZAKI

Abstract: The efficacy ofpolyvalent intravenous immunoglobulin therapy (IVIG) was evaluated in three patients with refractory myositis. Patients refractory to conventional therapy, such as corticosteroid administration, corticosteroid or cyclophosphamide pulse therapy [2 with dermatomyositis (DM), 1 with polymyositis (PM)] were treated with IVIG (0.4 g/kg daily) for 5 days. Clinical improvement was apparent within 1-2 months after IVIG and persisted for 19-23 months (DM patients) and 12 months (PM patient). No adverse …

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