Intravenous immunoglobulin in dermatology

Dhar, Sandipan

doi:10.4103/0019-5154.48996

Cited by 12 publications

(10 citation statements)

References 12 publications

(14 reference statements)

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“…Highdose IVIg is tapered maintaining the same dose but increasing the time interval between infusions. [40] Among all the treatment modalities in India, the most commonly used is steroids, either oral or in the form of pulse therapy. Non-steroidal immunosuppressive drugs are added as adjuvants to increase the efficacy and to have a steroid sparing effect.…”

Section: Treatmentmentioning

confidence: 99%

Bullous pemphigoid

Khandpur¹,

Verma²

2011

Indian J Dermatol Venereol Leprol

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Bullous pemphigoid (BP) is a relatively common autoimmune vesicobullous disease encountered in India. It is a subepidermal bullous disorder most commonly seen in the elderly and manifests as tense blisters on urticarial base, predominantly over flexures, and is associated with pruritus. The diagnosis can be confirmed by histology, direct and indirect immunofluorescence. Several new diagnostic techniques have also been developed. Treatment of BP is based on the extent and rate of progression of the disease. Several topical and systemic anti-inflammatory and immunosuppressive agents have been used with variable results.

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Section: Treatmentmentioning

confidence: 99%

Bullous pemphigoid

Khandpur¹,

Verma²

2011

Indian J Dermatol Venereol Leprol

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“…8 It seems IVIG is the best option for the management of TEN, because IVIG is human immunoglobulin and can strengthen the immune system. 9 An important issue in patients that IVIG is not affordable, as it is the case in our patient, or is contraindicated, in which one of immunosuppressive drugs can be used in the management of TEN during COVID-19 outbreak. As we know, there is not any study in COVID-19 outbreak to compare the effects of different immunosuppressive drugs such as cyclosporine and prednisolone on TEN patients.…”

Section: Discussionmentioning

confidence: 82%

Which immunosuppressive drug is preferred in the treatment of toxic epidermal necrolysis during COVID‐19 outbreak?

Farajzadeh

Ahramiyanpour

2021

Clinical Case Reports

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“…Intravenous immunoglobulin (IvIg; Dhar, ) is a sterile highly purified IgG preparation made from pooled human plasma and contains more than 95% of unmodified IgG and only trace amount of IgA or IgM. It has been used extensively in immunodeficiency diseases but its use in Dermatology is quite restricted because of lack of proper randomized control trials.…”

Section: Surgical Therapiesmentioning

confidence: 99%

Therapeutic options in vitiligo with special emphasis on immunomodulators: A comprehensive update with review of literature

Agarwal

Podder

Kassir

et al. 2020

Dermatologic Therapy

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Vitiligo is a relatively common disorder characterized by areas of depigmented skin. It may be associated with social stigma and adversely affects the quality of life. Although many treatment options are available, none is curable. The search continues for an effective therapeutic option. New targeted options include biologics and other immunomodulatory agents, with varying degrees of evidence. We have discussed briefly the therapeutic options with special emphasis on the newer immunomodulatory agents. We undertook a comprehensive English literature search across multiple databases such as PubMed, SCOPUS, EMBASE, MEDLINE, and Cochrane using keywords (alone and in combination) and MeSH items such as “vitiligo,” “treatment,” “recent,” and “immunomodulators” to obtain several relevant articles, priority being given to prospective randomized controlled trials. We scanned all the relevant articles and summarized them to obtain the latest information about the treatment of this condition to prepare the current article.

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Intravenous immunoglobulin in dermatology

Cited by 12 publications

References 12 publications

Bullous pemphigoid

Bullous pemphigoid

Which immunosuppressive drug is preferred in the treatment of toxic epidermal necrolysis during COVID‐19 outbreak?

Therapeutic options in vitiligo with special emphasis on immunomodulators: A comprehensive update with review of literature

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