Intravascular large B‐cell lymphoma in renal cell carcinoma incidentally detected by robot‐assisted partial nephrectomy

Abstract

Introduction Intravascular large B‐cell lymphoma is a rare and aggressive type of extranodal large B‐cell lymphoma. Although intravascular large B‐cell lymphoma can invade various organs, renal involvement has been rarely reported. Synchronous occurrence of intravascular lymphoma with renal cell carcinoma is extremely rare. We herein report a case of intravascular large B‐cell lymphoma in a renal cell carcinoma incidentally detected by robot‐assisted partial nephrectomy. Case presentation A 69‐year‐old female with recurrent fever lasting 4 years underwent robot‐assisted partial nephrectomy for small renal cell carcinoma. Histological findings led to the diagnosis of intravascular large B‐cell lymphoma, which involved the normal tissue of right kidney as well as clear cell renal cell carcinoma. She received six cycles of chemotherapy without major complications and achieved complete remission. Conclusion We encountered a rare case of synchronous intravascular lymphoma with renal cell carcinoma.

EBV-Positive Intravascular Large B-Cell Lymphoma of the Small Intestine: A Case Report and Literature Review

“…The nervous system and the skin are the most commonly affected areas. IVLBCL has been discovered in a growing number of tissues and organs, including the lungs, 13,14 breast, 15 uteri, 16 prostate, 17 liver, 18 kidneys, 19,20 and thyroid, 21 as awareness of the disease has increased. While this disease is uncommon in the gastrointestinal system, certain research has demonstrated that 8% (3 of 38) of IVLBCL patients manifest in the gastrointestinal system.…”

“…The most common sites are the nervous system and skin. However, with the gradual deepening of the understanding of the disease, IVLBCL has been found in an increasing number of tissues and organs, such as the lung [12,13] ,breast [14] ,uterus [15] ,prostate [16] ,liver [17] ,kidney [18,19] , and thyroid [20] . This disease is relatively rare in the gastrointestinal tract, but some studies have found that 8% (3/38) of IVLBCL case appear in the gastrointestinal tract [10] .…”