Intraprocedure contrast enhanced ultrasound: The value in assessing the effect of ultrasound-guided high intensity focused ultrasound ablation for uterine fibroids

Song, Peng; Hu, Liang; Chen, Wenzhi; Chen, Jin-Yun; Cai-yong, Yang; Wei, Xi; Zhang, Rong; Wang, Zhibiao; Zhang, Lian

doi:10.1016/j.ultras.2015.01.005

Cited by 26 publications

(20 citation statements)

References 22 publications

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“…The result shows that CEUS has the ability to show the size of fibroids and the nonperfused areas of the fibroid clearly. And the results from CEUS correlated well with the results obtained from MRI [13]. From those literature reviews, we know that both MRI and USI can be chosen to guide HIFU ablation.…”

Section: Introductionsupporting

confidence: 68%

An Ultrasound Imaging-Guided Robotic HIFU Ablation Experimental System and Accuracy Evaluations

Syu

Tseng

et al. 2017

Applied Bionics and Biomechanics

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In recent years, noninvasive thermal treatment by using high-intensity focused ultrasound (HIFU) has high potential in tumor treatment. The goal of this research is to develop an ultrasound imaging-guided robotic HIFU ablation system for tumor treatment. The system integrates the technologies of ultrasound image-assisted guidance, robotic positioning control, and HIFU treatment planning. With the assistance of ultrasound image guidance technology, the tumor size and location can be determined from ultrasound images as well as the robotic arm can be controlled to position the HIFU transducer to focus on the target tumor. After the development of the system, several experiments were conducted to measure the positioning accuracy of this system. The results show that the average positioning error is 1.01 mm with a standard deviation 0.34, and HIFU ablation accuracy is 1.32 mm with a standard deviation 0.58, which means this system is confirmed with its possibility and accuracy.

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Section: Introductionsupporting

confidence: 68%

An Ultrasound Imaging-Guided Robotic HIFU Ablation Experimental System and Accuracy Evaluations

Syu

Tseng

et al. 2017

Applied Bionics and Biomechanics

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“…15 According to previous studies, CEUS allows immediate assessment of the result of ablation and achieves similar results to those achieved by enhanced CT and enhanced MRI. [15][16][17][18] In our study, RFA achieved a non-enhanced region of over 70% of the initial lesion size when assessed by CEUS.…”

Section: Conservative Treatment Of Adenomyosis Is a Clinical Challengesupporting

confidence: 48%

“…Treatment is judged as a failure if there is nodular enhancement within the treated region in arterial phase and washout in late vascular phase. 18 A supplementary RFA was immediately performed in the enhanced regions. All patients received oral antibiotic prophylaxis for 3 days after the treatment.…”

Section: Ultrasound-guided Radiofrequency Ablation Proceduresmentioning

confidence: 99%

Ultrasound-guided transcervical radiofrequency ablation for symptomatic uterine adenomyosis

Nie

Hou

Ding

et al. 2017

BJR

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“…To increase the therapeutic efficiency of HIFU in achieving large ablation volume rapidly, various ultrasound contrast agents have been used with heating and cavitation effects, by modifying the acoustic environment in various tissues [8][9][10][11][12][13][14][15]. Among these, a phospholipid-shelled ultrasound contrast agent containing sulfur hexafluoride (SonoVue) is widely applied for diagnosis or evaluation after local ablation therapy in clinical settings, and assessed for enhancing the ablative effects of HIFU treatment [11,16,17]. Indeed, it was experimentally shown that SonoVue is effective in enhancing HIFU ablation in different tissues by enlarging the ablation volume [9], highly and rapidly increasing the temperature in the HIFU focal region [10,18], or decreasing the total energy of HIFU, to a certain volume of ablation [8].…”

Section: Discussionmentioning

confidence: 99%

Introducing clinical protocol for ultrasound-guided high-intensity focused ultrasound ablation of uterine fibroids in patients in Europe, provided from experienced Chinese center-prospective comparative

Dimitrov¹,

Zhou²,

Karamanliev³

et al. 2018

biomedicalresearch

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Introduction: This study aims to determine whether the Chinese clinical protocol, ultrasound guided high-intensity focused ultrasound (USgHIFU) combined with real-time monitoring using a contrast enhanced ultrasound (CEUS), also applies well in European patients with uterine fibroids. Methods: Seventy-five patients with 87 nodules of uterine fibroids from China and Bulgaria were treated with USgHIFU from April 2015 to July 2016, in the study. In Group A (Bulgarian) 26 (33 nodules) patients and in group B (Chinese) 49 (54 nodules) patients were included in the study. The same clinical procedure of USgHIFU treatment as well as a follow-up was performed on patients from China and Bulgaria. The general characteristics of the patients, the USgHIFU treatment and evaluation parameters, including; complications, fibroid size, tumor volume, subcutaneous fat size, non-perfused volume (NPV) and shrinkage process, were comparatively studied in Chinese and Bulgarian patients. Results: There were no significant differences in clinical parameters of Chinese and Bulgarian patients with uterine fibroids, such as vertical, left-right and аnterior-posterior size, treatment time, USgHIFU time.After USgHIFU treatment, no complications were recorded in both groups. On the 6 th and 12 th month after USgHIFU, fibroid nodules shrunk and the NPV was statistically significant compared to NPV before USgHIFU, but there were no statistically significant differences. Conclusions: The initial results of our study showed that CEUS clinical protocol for real time monitoring of efficacy and quality of the USgHIFU for uterine fibroid treatment that had been used in Chinese centers may also be applicable for European patients.

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Intraprocedure contrast enhanced ultrasound: The value in assessing the effect of ultrasound-guided high intensity focused ultrasound ablation for uterine fibroids

Cited by 26 publications

References 22 publications

An Ultrasound Imaging-Guided Robotic HIFU Ablation Experimental System and Accuracy Evaluations

An Ultrasound Imaging-Guided Robotic HIFU Ablation Experimental System and Accuracy Evaluations

Ultrasound-guided transcervical radiofrequency ablation for symptomatic uterine adenomyosis

Introducing clinical protocol for ultrasound-guided high-intensity focused ultrasound ablation of uterine fibroids in patients in Europe, provided from experienced Chinese center-prospective comparative

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