2010
DOI: 10.1007/s10549-010-1115-5
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Abstract: Conclusions -ELIOT appears a promising feature in early breast cancer treated with breast conserving surgery, reducing the exposure of normal tissues to radiations and shortening the radiation course from 6 weeks to one single session.3

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Cited by 194 publications
(120 citation statements)
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References 43 publications
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“…However, these contributions have not yet been incorporated into IOERT because of the restrictions that surgical conditions enforce. The treatment planning system reported here overcomes part of these limitations, offering the Breast cancer is a main indication for IOERT, inasmuch as random studies (8,9) are being carried out to demonstrate the equivalence with external fractionated radiotherapy in breast conserving surgery. Consequently, our results showing complete equivalence between the planning parameters for all the users are promising.…”
Section: Discussionmentioning
confidence: 99%
“…However, these contributions have not yet been incorporated into IOERT because of the restrictions that surgical conditions enforce. The treatment planning system reported here overcomes part of these limitations, offering the Breast cancer is a main indication for IOERT, inasmuch as random studies (8,9) are being carried out to demonstrate the equivalence with external fractionated radiotherapy in breast conserving surgery. Consequently, our results showing complete equivalence between the planning parameters for all the users are promising.…”
Section: Discussionmentioning
confidence: 99%
“…På den annen side er det en ulempe at flere kvinner må gjennomgå strålebehandling. Individualisert behandling i form av for eksempel intraoperativ stråleterapi kan bidra til å redusere denne ulempen (28,29). Årsakene til de fylkesvise forskjellene i bruk av brystbevarende teknikk bør identifiseres og følges opp i henhold til anbefalingene fra Norsk Bryst Cancer Gruppe.…”
Section: Lk-63unclassified
“…Attention should be paid to ensure negative margins on final pathology (Beal et al, 2007), although margin positivity does not always influence the rate of local recurrences if effective radiotherapy is delivered (Chism et al, 2006;Mariani et al, 1998;Veronesi et al, 2010). Intraoperative frozen sections may be used to reduce positive margins (Fukamachi et al, 2010).…”
Section: Pathologymentioning
confidence: 99%
“…Tumors with higher tumor grade is not suitable for PBI, because it is one of risk factors for local recurrence and most prospective trials have not considered as eligibility criteria. As for the tumor characteristics biologically, such as HER2-type or basal-type have been shown to involve higher risk for local recurrence than luminal A or B-types (Kyndi et al, 2008;Nguyen et al, 2008;Veronesi, et al, 2010), then tailored local-regional treatment for early-stage breast cancer has been reported to be mandatory now (Solin, 2010).…”
Section: Pathologymentioning
confidence: 99%