Intraneural lipoma of the radial nerve presenting as Wartenberg syndrome: A case report and review of literature

Intraneural lipomatous tumor of the median nerve: Three case reports with a review of literature

“…5 To our knowledge, not so many cases have been reported in the English literature as intraneural lipomas. 2,[4][5][6][7][8][9] The intraneural lipoma tends to occur in the fourth and fifth decades and has a female predominance. Most of the intraneural lipoma occurs in the median nerve, while also reported to occur in the radial nerve, 2 sciatic nerve, 7 ulnar nerve, 8 and posterior interosseous nerve.…”

“…2 Intraneural lipomas are usually well encapsulated with nerve fibers that run on the outer surface of the mass; thus, complete excision without damage to the adjoining nerve is possible. On the other hand, fibrolipomatous hamartoma of the nerve is composed of fibrous tissues, fatty tissues, and normal nerve fibers, making complete excision without nerve damage difficult.…”

Intraneural lipoma of the median nerve mimicking carpal tunnel syndrome

“…As the lesions grow, they may cause pain and symptoms consistent with compression neuropathy [3,5,6] and they may frequently be misdiagnosed as very more common compression neuropathy syndromes such as carpal tunnel syndrome; while the prevalence of clinically and electrophysiologically confirmed carpal tunnel syndrome is approximately 2-3% [2], a PubMed search for "intraneural lipoma" actually returns about 20 results, most of which are case reports.…”

“…With a predominance of affected females, true lipomas show a peak incidence during the fourth and fifth decades [3]. They are encapsulated, non-invasive tumours that displace adjacent structures, from which they can be easily dissected due to the presence of a good cleavage plane.…”

“…Even though it is termed intraneural, the pathology probably arises in the epineurium, where fat cells and fibroblasts proliferate, and then infiltrate between nerve bundles [3,9].…”