2007
DOI: 10.1001/archderm.143.7.841
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Intralesional Bleomycin for Angiolymphoid Hyperplasia

Abstract: A 51-year-old woman presented with a 4-year history of slightly pruritic, bleeding papules on her right ear. Approximately 2 years earlier, the lesions had been excised, but they had recurred the following year and had increased in number within the past 3 months. The dermatologic examination revealed 5 violaceous, erythematous soft papules ranging from 3 mm to 1 cm in diameter in the helix and on the upper lateral postauricular region of the right ear (Figure 1). The results of the systemic examination were n… Show more

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Cited by 22 publications
(14 citation statements)
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“…The most common therapeutic options are surgical excision and pulse dye laser. Intralesional injections of glucocorticoids, interferon alfa-2a, and cytotoxic agents, electrodesiccation and cryotherapy have also been reported as therapeutic options with variable levels of success (2,6). Our patient was treated with cryotherapy and only partial regression was observed after 2 months.…”
Section: Casementioning
confidence: 65%
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“…The most common therapeutic options are surgical excision and pulse dye laser. Intralesional injections of glucocorticoids, interferon alfa-2a, and cytotoxic agents, electrodesiccation and cryotherapy have also been reported as therapeutic options with variable levels of success (2,6). Our patient was treated with cryotherapy and only partial regression was observed after 2 months.…”
Section: Casementioning
confidence: 65%
“…It mainly occurs in the third to fourth decades of life, with a higher incidence in women. The most common sites are the head and neck, particularly the region around the ears (6). There is controversy regarding whether it is a true vascular neoplasm or a reactive healing process secondary to damage to an artery or vein following a variety of insults.…”
Section: Casementioning
confidence: 99%
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“…Jedoch ist bei der ALHE in bis zu 20 % der Fälle auch das Auftreten einer Lymphadenopathie und/oder einer Blut-Eosinophilie möglich [4,13]. Einzelfälle mit deutlich erhöhtem Serum-IgE wurden ebenfalls beschrieben [14].…”
Section: üBerlappungssyndromunclassified
“…Die therapeutischen Möglichkeiten zur Limitierung der ALHE umfassen ein operatives Vorgehen, eine ablative Laserung mittels Neodym:YAG-Laser oder eine Kryotherapie. Alternativ wurden Therapien mit topischen oder intraläsionalen Kortikosteroiden, Retinoiden, Interferon-a2b, Imiquimod, intraläsionalen Chemotherapeutika und Radiotherapie beschrieben [9,13]. Beim Morbus Kimura kommen neben einer kontrolliert beobachtenden Strategie ebenfalls die operative Therapie, die Radiotherapie oder die Gabe von systemischen Kortikosteroiden in Frage.…”
Section: Therapieunclassified