1991
DOI: 10.1111/j.1365-2826.1991.tb00257.x
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Abstract: Key words: growth hormone, mu-, kappa-and delta-opioid receptors, basal and anterior hypothalamus. AbstractThe possible effects of opioid receptor agonists on growth hormone (GH)-releasing factor or somatostatin neurons were examined by measuring the effects of localized intracerebral injections of mu-, delta-and kappa-selective agonists on GH secretion, Serial GH concentrations were measured in plasma in unanaesthetized male rats chronically prepared with venous and intracerebral cannulae, before and after tr… Show more

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Cited by 5 publications
(2 citation statements)
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“…b Data also in [7], c This dose was used in the interaction study. [12]. b Data also in [7], c This dose was used in the interaction study.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…b Data also in [7], c This dose was used in the interaction study. [12]. b Data also in [7], c This dose was used in the interaction study.…”
Section: Resultsmentioning
confidence: 99%
“…Drugs injected were clonidine HCI (Sigma, St. Louis, Mo., USA), the opioid u receptor agonist Tv r -O -AI a -GI y -(M e) Ph e -GI yol (DAGO; Bachem, Bubendorf, Switzerland) and quipazine dimaleate (Research Biochemicals, Natick, Mass., USA). DAGO was used instead of morphine (which we used in the intravenous interac tion study), because it is also predominantly a u receptor agonist [II], and we had previously shown that it increases GH levels when injected into the hypothalamus [12]. Those drugs found to signifi cantly increase GH levels were then injected in combination.…”
Section: Experimental Designmentioning
confidence: 99%