Intradermal Tests in Relation to Arsphenamine Dermatitis

Experimental Arsphenamine Dermatitis

“…The detection of sensitivity by means of the intcracermal test has largely been discredited.7 8 The sensitizing action of a single intradermal or * From the Section on Dermatology, Department of Medicine, Royal Victoria Hospital, Montreal, Canada. paravenous injection of arsphenamine in humans has been emphasized by many workers,9' 10, 11 and undoubtedly occurs. The variability of this response was recently noted by Schock.12 He was unable to produce dermatitis in 101 patients in whom a preliminary sensitizing injection was followed after intervals of five to ten weeks with intravenous arsphenamine therapy.…”