Intradermal hepatitis B vaccination in patients with advanced chronic renal failure: immunogenicity and follow‐up

Abstract

Intradermal hepatitis B virus vaccination is an alternative in end-stage renal failure.

Meta-Analysis: The Impact of Nutritional Status on the Immune Response to Hepatitis B Virus Vaccine in Chronic Kidney Disease

“…An extensive review of the medical literature on this topic revealed numerous reports [18][19][20][21][22][23][24] promoting a link between impaired response to HBV vaccine and poor nutritional status, as detected by low serum albumin [18][19][20][21]24], body weight [22], or normalized protein nitrogen appearance [23] in the CKD population. These studies were not included in our study due to a lack of a modern statistical analysis.…”

“…One study reported by multivariate analysis a significant and independent relationship between poor nutritional status and failure to seroconvert after HBV vaccination among dialysis patients but was excluded as aRR and 95% CI were not given [17]. At least seven reports [18][19][20][21][22][23][24] found a significant relationship between under-nutrition, as assessed mostly by serum albumin levels, and failure to develop anti-HBs antibody after HBV vaccination but were not included as only univariate analysis was carried out. There was a 100% concordance between reviewers with respect to final inclusion and exclusion of studies reviewed based on the predefined inclusion and exclusion criteria.…”

Levamisole as an adjuvant to hepatitis B vaccination in patients with chronic kidney disease

“…29 Of these side-effects, it is possible to mention to itching, hyperpigmentation, myalgia, headache, and nausea which in none of the studies were in a level causing to stop injecting the vaccine or levamisole pill. [30][31][32] Furthermore in our study, vaccination was stopped in none of the cases due to possible side-effects. No specific side-effect of using levamisole pill was observed in group A.…”

Sex bias in response to hepatitis B vaccination in end-stage renal disease patients: Meta-analysis

“…After excluding studies not fulfilling inclusion criteria, 19 clinical trials [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] have been remained whose demoKhedmat H et al . Sex and HBV vaccine immunogenicity graphic data is summarized in Table 1.…”