Intracellular calcium injection causes increased potassium conductance in Aplysia nerve cells

Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.

“…These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

“…Our data clearly show that a presumed increase of [Ca2+], using the ionophore A23187 decreases the purinergic and the f8-adrenergic-induced K+ current while a chelation with EGTA of the intracellular free Ca2+ increases it. These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.

“…These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

“…Our data clearly show that a presumed increase of [Ca2+], using the ionophore A23187 decreases the purinergic and the f8-adrenergic-induced K+ current while a chelation with EGTA of the intracellular free Ca2+ increases it. These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

Post‐stimulus hyperpolarization and slow potassium conductance increase in Aplysia giant neurone

“…Pressure-injection of Ca into the giant-cell soma of Aply8ia causes an increase in K conductance (Meech & Strumwasser, 1970). The reversal potential for the Ca-induced hyperpolarization (-62 mV) was close to that which we observed for PSH (see Figs.…”

Intracellular calcium and extra‐retinal photoreception in Aplysia giant neurons

“…Therefore, we reinvestigated the effects of TEA upon the potassium conductance activated by the intracellular injection of calcium in Rz and its homolog in the left pleural ganglion. We confirmed the earlier reports of Meech (1972) and Brown and Brown (1973) that intracellular injection of calcium increased membrane conductance. In agreement with Meech (1972), when the driving force for the calcium-activated potassium current was outwards TEA reduced conductance, but when the driving force was inwards, TEA had little effect.…”

Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.

“…These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

“…Our data clearly show that a presumed increase of [Ca2+], using the ionophore A23187 decreases the purinergic and the f8-adrenergic-induced K+ current while a chelation with EGTA of the intracellular free Ca2+ increases it. These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

Post‐stimulus hyperpolarization and slow potassium conductance increase in Aplysia giant neurone

“…Pressure-injection of Ca into the giant-cell soma of Aply8ia causes an increase in K conductance (Meech & Strumwasser, 1970). The reversal potential for the Ca-induced hyperpolarization (-62 mV) was close to that which we observed for PSH (see Figs.…”

Intracellular calcium and extra‐retinal photoreception in Aplysia giant neurons

“…Therefore, we reinvestigated the effects of TEA upon the potassium conductance activated by the intracellular injection of calcium in Rz and its homolog in the left pleural ganglion. We confirmed the earlier reports of Meech (1972) and Brown and Brown (1973) that intracellular injection of calcium increased membrane conductance. In agreement with Meech (1972), when the driving force for the calcium-activated potassium current was outwards TEA reduced conductance, but when the driving force was inwards, TEA had little effect.…”

Cyclic adenosine monophosphate, calcium, acetylcholine and the current induced by adenosine in the Xenopus oocyte.

“…These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

“…Our data clearly show that a presumed increase of [Ca2+], using the ionophore A23187 decreases the purinergic and the f8-adrenergic-induced K+ current while a chelation with EGTA of the intracellular free Ca2+ increases it. These results are just opposite to the well known calcium-dependent potassium conductance (Meech, 1972) and to the calcium-dependent chloride conductance more recently described in several preparations including the oocyte (Miledi, 1982;Barish, 1983;Miledi & Parker, 1984).…”

Post‐stimulus hyperpolarization and slow potassium conductance increase in Aplysia giant neurone

“…Pressure-injection of Ca into the giant-cell soma of Aply8ia causes an increase in K conductance (Meech & Strumwasser, 1970). The reversal potential for the Ca-induced hyperpolarization (-62 mV) was close to that which we observed for PSH (see Figs.…”

Intracellular calcium and extra‐retinal photoreception in Aplysia giant neurons

“…Therefore, we reinvestigated the effects of TEA upon the potassium conductance activated by the intracellular injection of calcium in Rz and its homolog in the left pleural ganglion. We confirmed the earlier reports of Meech (1972) and Brown and Brown (1973) that intracellular injection of calcium increased membrane conductance. In agreement with Meech (1972), when the driving force for the calcium-activated potassium current was outwards TEA reduced conductance, but when the driving force was inwards, TEA had little effect.…”