Intoxication par le poisson coffre

Ababou, A.; Mosadik, A.; Squali, J; Fikri, K. O.; Lazreq, C.; Sbihi, A.

doi:10.1016/s0750-7658(00)00195-7

Cited by 7 publications

(3 citation statements)

References 9 publications

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“…Histopathological alterations in hepatocytes due to cyanotoxin exposure had already been described by some researchers, who studied cytoskeleton destruction caused by increased levels of protein phosphorylation after exposure to the toxin (47)(48)(49).…”

Section: Discussionmentioning

confidence: 80%

Oxidative stress and hepatotoxicity in rats induced by poisonous pufferfish (Lagocephalus lagocephalus) meat

Saoudi¹,

Abdelmouleh²,

Ellouze³

et al. 2009

J. Venom. Anim. Toxins incl. Trop. Dis

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ABSTRACT:This study was undertaken to evaluate the effect of pufferfish (Lagocephalus lagocephalus) meat poisoning on hepatic functions of Wistar rats. For this purpose, groups of rats (Lcr, Lcu+b and Lcu-b) received diet supplemented with 10% of raw or cooked meat, respectively, with or without cooking water of L. lagocephalus while groups Mcr and Mcu+b received diet supplemented with 10% of raw or cooked meat of Liza aurata, which were used as a negative control. In Lcu+b group, ALT, AST and ALP rates (hepatic enzyme markers) decreased after two months of treatment, indicating liver damage. We also observed an increase of 54 and 65% of thiobarbituric acid reactive substances (TBARS) in their livers respectively 48 hours and two months after treatment compared to controls. The catalase (CAT) activity in group Lcu+b decreased (p < 0.05) after two periods of treatment, whereas metallothionein (MT) level significantly increased and decreased, respectively after 48 hours and two months. In fact, in the histological analysis of the livers from Lcu+b treated group, we observed an increase in vacuolisation, necrosis, hepatocytes ballooning and sinusoids dilation. These results indicate that L. lagocephalus meat cooked with water produces hepatotoxicity and oxidative damage.

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Section: Discussionmentioning

confidence: 80%

Oxidative stress and hepatotoxicity in rats induced by poisonous pufferfish (Lagocephalus lagocephalus) meat

Saoudi¹,

Abdelmouleh²,

Ellouze³

et al. 2009

J. Venom. Anim. Toxins incl. Trop. Dis

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“…Until recently, TTX was believed to be confined to East Asia, but recent studies have shown that fish containing the toxin have been found in other regions of the Pacific and the Indian Ocean, as well as the Mediterranean Sea [3]. There are also many poisoning cases reported from countries, such as Australia [167,168], New Caledonia [169], Brazil [170,171], Mexico [172], Oman [173], Madagascar [174], Reunion Island [175], Egypt [176], and Morocco [177].…”

Section: Global Cases Of Ttx Intoxication In Humansmentioning

confidence: 99%

“…Poisonous fish were not an issue of concern in Mediterranean countries until recently. In terms of TTX poisoning, among many species that entered the Mediterranean Sea and settled into its ecosystem, pufferfish, known for their poisonous characteristics, are of special concern [177]. TTX appearance is a rather recent phenomenon for Mediterranean countries as the silver stripe blaasop (L. sceleratus (Gmelin, 1789)) invaded the Mediterranean Sea.…”

Section: Global Cases Of Ttx Intoxication In Humansmentioning

confidence: 99%

An Updated Review of Tetrodotoxin and Its Peculiarities

et al. 2022

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Tetrodotoxin (TTX) is a crystalline, weakly basic, colorless organic substance and is one of the most potent marine toxins known. Although TTX was first isolated from pufferfish, it has been found in numerous other marine organisms and a few terrestrial species. Moreover, tetrodotoxication is still an important health problem today, as TTX has no known antidote. TTX poisonings were most commonly reported from Japan, Thailand, and China, but today the risk of TTX poisoning is spreading around the world. Recent studies have shown that TTX-containing fish are being found in other regions of the Pacific and in the Indian Ocean, as well as the Mediterranean Sea. This review aims to summarize pertinent information available to date on the structure, origin, distribution, mechanism of action of TTX and analytical methods used for the detection of TTX, as well as on TTX-containing organisms, symptoms of TTX poisoning, and incidence worldwide.

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Family tetrodotoxin poisoning in Reunion Island (Southwest Indian Ocean) following the consumption of Lagocephalus sceleratus (Pufferfish)

Puech

Batsalle

Roget

et al. 2014

Bull. Soc. Pathol. Exot.

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Pufferfish poisoning has rarely been reported in the southwestern Indian Ocean and in the French overseas territories. In Reunion Island, the last notified documented case occurred in 1989 and people are no longer aware of the potential toxicity of pufferfish. We report a family hospitalized for a tetrodotoxin poisoning following the consumption of Lagocephalus sceleratus caught on the coast of Reunion Island in September 2013. Two patients presenting acute vital functions failures were admitted in an ICU. Ten people were admitted simultaneously to the emergency department after consuming L. sceleratus with signs of toxicity appearing within 2 hours. Treatment was supportive, but included the need for mechanical ventilation for two patients. All those affected had complete and uneventful recoveries within a few days. The fish consumed was identified as L. sceleratus, a species known to contain tetrodotoxin. The diagnosis of tetrodotoxin poisoning was suggested by typical clinical manifestations together with the history of very recent consumption of tetrodotoxin-containing fish. Tetrodotoxin was later detected at high levels in food remnants. To the best of our knowledge, there has been no documented case series of tetrodotoxin poisoning reported from Reunion Island for the last 25 years and from the entire Indian Ocean area since 1998. Pufferfish intoxication is one of the most common causes of poisoning among people in coastal regions of Asia but it has also recently been reported in areas where it was previously unknown, particularly along the Mediterranean shores and in Spain. Public health education in French overseas territories and along the Mediterranean shores should be adapted to include increased awareness of the danger of consuming pufferfish. Health teams must be aware of such clinical presentations.

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Intoxication par le poisson coffre

Cited by 7 publications

References 9 publications

Oxidative stress and hepatotoxicity in rats induced by poisonous pufferfish (Lagocephalus lagocephalus) meat

Oxidative stress and hepatotoxicity in rats induced by poisonous pufferfish (Lagocephalus lagocephalus) meat

An Updated Review of Tetrodotoxin and Its Peculiarities

Family tetrodotoxin poisoning in Reunion Island (Southwest Indian Ocean) following the consumption of Lagocephalus sceleratus (Pufferfish)

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