Intestinal parasitic infections and associated risk factors in preschoolers from different urban settings in Central-Western Brazil

Luz, João Gabriel Guimarães; Carvalho, Amanda Gabriela de; Marques, Aline Pereira; Marcondes, Alyna Araújo; Roma, José Henrique Francisco; Castro, Ludiele Souza; Dias, João Víctor Leite; Pavoni, Juliana Helena Chávez

doi:10.12980/apjtd.7.2017d7-90

Cited by 10 publications

(10 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In Rondonópolis, the periphery generally corresponds to areas of recent colonization, and it is bordered by pastures or green areas. These scenarios are probably a consequence of the recent accelerated urbanization process, migration waves and population growth, which led to the disorderly occupation of the natural space with formation of areas marked by poor living conditions as well as deficient sanitary and urban infrastructure [23]. Taken together, these factors probably favored the high adaptation of the vector [7], leading to the establishment of VL transmission cycles in such peripheral zones, as similarly reported in Teresina, Piauí State [48].…”

Section: Resultsmentioning

confidence: 63%

“…The territory has an area of 4686.622 km², of which 129.2 km² is allocated for the urban area [29]. This urban area is composed of 449 census tracts and 237 neighborhoods that have marked socioeconomic and environmental intra-urban differences [23,30]. Human VL is highly endemic to this locality [7], with 210 autochthonous human cases reported between 2003 and 2016 [9].…”

Section: Study Areamentioning

confidence: 99%

“…The prevalence of CVL has been reported in several Brazilian regions [15][16][17][18][19]. However, since VL occurrence is usually associated with socioeconomic and environmental characteristics [20,21], there is still a need to consider such aspects during the determination of the prevalence of canine disease, mainly because Brazilian cities present remarkable intra-urban differences that may influence its occurrence [22,23].…”

Section: Study Areamentioning

confidence: 99%

See 2 more Smart Citations

High seroprevalence and peripheral spatial distribution of visceral leishmaniasis among domestic dogs in an emerging urban focus in Central Brazil: a cross-sectional study

Carvalho

Luz

Rodrigues

et al. 2018

Pathogens and Global Health

Self Cite

View full text Add to dashboard Cite

The Brazilian municipality of Rondonópolis is an emerging urban focus of intense transmission of visceral leishmaniasis (VL), where few investigations have addressed canine reservoirs. This study assessed the seroprevalence and spatial distribution of canine visceral leishmaniasis (CVL) in the urban area of Rondonópolis. A CVL serosurvey was conducted between October 2016 and February 2017 using an immunochromatographic rapid test and enzyme-linked immunosorbent assay. Domestic dogs were sampled from 25 heterogeneous regions previously defined by the Spatial 'K'luster Analysis by Tree Edge Removal algorithm, which considered the socioeconomic and environmental features from the last demographic census. The CVL spatial distribution was analyzed by kernel density estimation (KDE) and spatial scan statistic. All the autochthonous human VL cases reported between 2014 and 2016 were georeferenced. Of the 600 dogs tested, 115 were seropositive in both tests. The overall CVL prevalence was 19.2% (95%CI: 16.1-22.3%), which varied widely among the evaluated regions (0.0-35.1%). Almost 25% of the sampled households (n = 405) had at least one infected dog. KDE demonstrated that positive CVL households were concentrated in the peripheral areas of the city. Spatial scan statistics detected a spatial cluster with significantly low CVL prevalence in the central region (relative risk = 0.37; p = 0.04), where only one human VL case was reported. Thus, we demonstrated a high prevalence of CVL in domestic dogs from diverse socioeconomic and environmental urban contexts in Rondonópolis. The CVL cases were peripherally distributed and occurred more frequently in areas that had reported human VL.

show abstract

Section: Resultsmentioning

confidence: 63%

Section: Study Areamentioning

confidence: 99%

Section: Study Areamentioning

confidence: 99%

See 1 more Smart Citation

High seroprevalence and peripheral spatial distribution of visceral leishmaniasis among domestic dogs in an emerging urban focus in Central Brazil: a cross-sectional study

Carvalho

Luz

Rodrigues

et al. 2018

Pathogens and Global Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…Isso representou outra alteração considerável no panorama da LV na área de estudo, uma vez que a região metropolitana da capital Cuiabá havia liderado os registros entre 1998 e 2005 (MESTRE; FONTES, 2007). A elevada ocorrência de LV em Rondonópolis parece estar associada ao intenso processo de crescimento populacional e descontrolada ocupação do espaço geográfico com formação de áreas com marcantes diferenças intraurbanas recentemente visualizados no município (CARVALHO et al, 2018;LUZ et al, 2017;LUZ et al, 2018). Aparentemente, isso pode ter favorecido a adaptação dos insetos vetores na área urbana, que juntamente com a presença de reservatórios domésticos e seres humanos susceptíveis, favoreceu a instalação de ciclos de transmissão .…”

Section: Discussionunclassified

Abordagens Geográfica da Vigilância, Prevenção e Promoção da Saúde

2019

View full text Add to dashboard Cite

“…The predominance of VL among urban residents is consistent with the expansion of the disease to large cities observed in Brazil since the 1980s, mainly due to demographic, environmental, and sanitary factors 2 , 19 . In Rondonópolis , this process began in the 2000s and may have been influenced by the disorderly growth of the city, migration waves, accelerated population increase, expansion of agriculture, industrialization and the emergence of spaces with marked intra-urban differences 43 , as detected in other regions of the country 19 , 34 , 35 , 38 .…”

Section: Discussionmentioning

confidence: 99%

Visceral leishmaniasis in a Brazilian endemic area: an overview of occurrence, HIV coinfection and lethality

Luz

Naves

Carvalho

et al. 2018

Rev. Inst. Med. trop. S. Paulo

Self Cite

View full text Add to dashboard Cite

The Brazilian municipality of Rondonópolis, Mato Grosso State, represents an important visceral leishmaniasis (VL) endemic area. This study described epidemiological and clinical aspects of the occurrence, VL/HIV coinfection and lethality related to VL in Rondonópolis. Data from autochthonous cases reported between 2011 and 2016 were obtained from official information systems. During this period, 81 autochthonous cases were reported, with decreasing incidence through 2016. Contrastingly, the lethality rate was 8.6% overall, but varied widely, reaching a peak (20%) in 2016. Almost 10% of patients had VL/HIVcoinfection. The occurrence of VL prevailed among men (56.8%), brown-skinned (49.4%), urban residents (92.6%), aged 0-4 years (33.3%). Housewives or retired (29.6%) were the most affected occupational groups. Lower age was the main difference among the total VL cases and those who were coinfected or died. Clinically, fever, weakness and splenomegaly were more frequent among all VL cases and VL/HIV coinfected individuals. Bacterial infections (p=0.001) and bleeding (p<0.001) were associated with death due to VL. Pentavalent antimonial and liposomal amphotericin B were the first choices for treatment among all VL cases (71.6%) and those who died (71.4%), respectively. VL/HIV patients were equally treated with both drugs. These findings may support control measures and demonstrate the need for further investigations.

show abstract

Intestinal parasitic infections and associated risk factors in preschoolers from different urban settings in Central-Western Brazil

Cited by 10 publications

References 24 publications

High seroprevalence and peripheral spatial distribution of visceral leishmaniasis among domestic dogs in an emerging urban focus in Central Brazil: a cross-sectional study

High seroprevalence and peripheral spatial distribution of visceral leishmaniasis among domestic dogs in an emerging urban focus in Central Brazil: a cross-sectional study

Abordagens Geográfica da Vigilância, Prevenção e Promoção da Saúde

Visceral leishmaniasis in a Brazilian endemic area: an overview of occurrence, HIV coinfection and lethality

Contact Info

Product

Resources

About