Intestinal microbiota and HIV-1 infection

Abstract

ABSTRACT:The intestinal microbiota consists of a qualitatively and quantitatively diverse range of microorganisms dynamically interacting with the host. It is remarkably stable with regard to the presence of microorganisms and their roles which, however, can be altered due to pathological conditions, diet composition, gastrointestinal disturbances and/or drug ingestion. The present review aimed at contributing to the discussion about changes in the intestinal microbiota due to HIV-1 infection, focusing on the triad infection-microbiota-nutrition as factors that promote intestinal bacterial imbalance. Intestinal microbiota alterations can be due to the HIV-1 infection as a primary factor or the pharmacotherapy employed, or they can be one of the consequences of the disease.

Application of SSM in the Distribution Chain of Antiretroviral Medicines

“…CATWOE is elaborated under the exploration and incorporation of the various points of view and with several individuals who will decide on the research problem (Ministry of Health, 2007). At this stage, an analysis of the situation must be carried out in depth, to identify, in the perception of the actors involved, the means and ends of the specific problem (Trindade et al, 2007).…”