2018
DOI: 10.18632/aging.101393
View full text |Buy / Rent full text
|
Sign up to set email alerts
|

Abstract: Hypopituitary dwarf mice demonstrate advantages of longevity, but little is known of their colon development and intestinal immunity. Herein we found that Ames dwarf mice have shorter colon and colonic crypts, but larger ratio of mesenteric lymph nodes (MLNs) over body weight than age-matched wild type (WT) mice. In the colonic lamina propria (cLP) of juvenile Ames mice, more inflammatory neutrophils (Ā: 0.15% vs. 0.03% in WT mice) and monocytes (Ā: 7.97% vs. 5.15%) infiltrated, and antigen presenting cells CD… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
1

Relationship

1
0

Authors

Journals

citations
Cited by 6 publications
(1 citation statement)
references
References 36 publications
(31 reference statements)
0
1
0
Order By: Relevance
“…Colonic epithelial crypts and lamina propria cells were isolated as previously reported ( 22 ). Briefly, the colon was cut into small pieces and shaken twice for 20 min each in HBSS buffer supplemented with 2% FBS, 5 mM EDTA and 1 mM DTT.…”
Section: Methodsmentioning
confidence: 99%