Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria

Abstract

BackgroundPregnancy hyperglycaemia without meeting gestational diabetes mellitus (GDM) diagnostic criteria affects a significant proportion of pregnant women each year. It is associated with a range of adverse pregnancy outcomes. Although intensive management for women with GDM has been proven beneficial for women and their babies, there is little known about the effects of treating women with hyperglycaemia who do not meet diagnostic criteria for GDM and type 2 diabetes (T2DM). ObjectivesTo assess the effects of different types of management strategies for pregnant women with hyperglycaemia not meeting diagnostic criteria for GDM and T2DM (referred as borderline GDM in this review). Search methodsWe searched the Cochrane Pregnancy and Childbirth Group's Trials Register (30 September 2011). Selection criteriaRandomised and cluster-randomised trials comparing alternative management strategies for women with borderline GDM. Data collection and analysisTwo review authors independently assessed study eligibility, extracted data and assessed risk of bias of included studies. Data were checked for accuracy.1 Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteria (Review)

Pregnant Women Become Sweeter: A Population-Based Study of Trends in Glucose Challenge Test Results Over a Decade

“…11,19 Moreover, emerging data indicate that high normal GCT (>125 mg/dL) is similarly associated with poorer perinatal outcome. 9 –14 The results of this study showed an increase in incidence of abnormal GCT (>140 mg/dL) from 10.6% to 18.1% one decade later ( p < 0.001). Although mean age during pregnancy also increased (from 28 to 30) over that period, a multivariable logistic model revealed that trends over the years were independent of the rise in maternal age.…”

Pregnant Women Become Sweeter: A Population-Based Study of Trends in Glucose Challenge Test Results Over a Decade

“…11,19 Moreover, emerging data indicate that high normal GCT (>125 mg/dL) is similarly associated with poorer perinatal outcome. 9 –14 The results of this study showed an increase in incidence of abnormal GCT (>140 mg/dL) from 10.6% to 18.1% one decade later ( p < 0.001). Although mean age during pregnancy also increased (from 28 to 30) over that period, a multivariable logistic model revealed that trends over the years were independent of the rise in maternal age.…”

Antenatal interventions to reduce preterm birth: an overview of Cochrane systematic reviews

“…The latter effect could not be observed in the specific analysis of oral beta-blockers for women with mild to moderate hypertension, but in this comparison the intervention group was more likely to give birth to SGA babies [38]. No statistically significant group differences in primary or secondary outcomes were reported for the remaining five interventions [29,33,36,40,41]. …”

“…Seven reviews either addressed the prevention [22,23], the detection [24] or the treatment of infection [25-28] (Additional file 3: Table S1c). Twelve reviews analysed effects of various interventions applied for the prevention [29-36] or the treatment [37-40] of hypertensive disorders/pre-eclampsia; one review focused on interventions for pregnant women with hyperglycaemia [41] (Additional file 3: Table S1d). Eleven reviews covered general effects of dietary interventions on pregnancy outcomes [42-52] (Additional file 3: Table S1e).…”

Prevalence and risk factors of gestational diabetes mellitus in a population of pregnant women attending three health facilities in Limbe, Cameroon: a cross-sectional study

“…The real prevalence of GDM is not known but varies from one geographic region to another. Secondly, the diagnostic criteria used by most studies are not similar [21, 30]. However, the high prevalence of GDM in our study may be attributed to the fact that the population under study falls within the high-risk group for diabetes mellitus (African).…”

Pregnant Women Become Sweeter: A Population-Based Study of Trends in Glucose Challenge Test Results Over a Decade

“…11,19 Moreover, emerging data indicate that high normal GCT (>125 mg/dL) is similarly associated with poorer perinatal outcome. 9 –14 The results of this study showed an increase in incidence of abnormal GCT (>140 mg/dL) from 10.6% to 18.1% one decade later ( p < 0.001). Although mean age during pregnancy also increased (from 28 to 30) over that period, a multivariable logistic model revealed that trends over the years were independent of the rise in maternal age.…”

Antenatal interventions to reduce preterm birth: an overview of Cochrane systematic reviews

“…The latter effect could not be observed in the specific analysis of oral beta-blockers for women with mild to moderate hypertension, but in this comparison the intervention group was more likely to give birth to SGA babies [38]. No statistically significant group differences in primary or secondary outcomes were reported for the remaining five interventions [29,33,36,40,41]. …”

“…Seven reviews either addressed the prevention [22,23], the detection [24] or the treatment of infection [25-28] (Additional file 3: Table S1c). Twelve reviews analysed effects of various interventions applied for the prevention [29-36] or the treatment [37-40] of hypertensive disorders/pre-eclampsia; one review focused on interventions for pregnant women with hyperglycaemia [41] (Additional file 3: Table S1d). Eleven reviews covered general effects of dietary interventions on pregnancy outcomes [42-52] (Additional file 3: Table S1e).…”

Prevalence and risk factors of gestational diabetes mellitus in a population of pregnant women attending three health facilities in Limbe, Cameroon: a cross-sectional study

“…The real prevalence of GDM is not known but varies from one geographic region to another. Secondly, the diagnostic criteria used by most studies are not similar [21, 30]. However, the high prevalence of GDM in our study may be attributed to the fact that the population under study falls within the high-risk group for diabetes mellitus (African).…”

Pregnant Women Become Sweeter: A Population-Based Study of Trends in Glucose Challenge Test Results Over a Decade

“…11,19 Moreover, emerging data indicate that high normal GCT (>125 mg/dL) is similarly associated with poorer perinatal outcome. 9 –14 The results of this study showed an increase in incidence of abnormal GCT (>140 mg/dL) from 10.6% to 18.1% one decade later ( p < 0.001). Although mean age during pregnancy also increased (from 28 to 30) over that period, a multivariable logistic model revealed that trends over the years were independent of the rise in maternal age.…”

Antenatal interventions to reduce preterm birth: an overview of Cochrane systematic reviews

“…The latter effect could not be observed in the specific analysis of oral beta-blockers for women with mild to moderate hypertension, but in this comparison the intervention group was more likely to give birth to SGA babies [38]. No statistically significant group differences in primary or secondary outcomes were reported for the remaining five interventions [29,33,36,40,41]. …”

“…Seven reviews either addressed the prevention [22,23], the detection [24] or the treatment of infection [25-28] (Additional file 3: Table S1c). Twelve reviews analysed effects of various interventions applied for the prevention [29-36] or the treatment [37-40] of hypertensive disorders/pre-eclampsia; one review focused on interventions for pregnant women with hyperglycaemia [41] (Additional file 3: Table S1d). Eleven reviews covered general effects of dietary interventions on pregnancy outcomes [42-52] (Additional file 3: Table S1e).…”

Prevalence and risk factors of gestational diabetes mellitus in a population of pregnant women attending three health facilities in Limbe, Cameroon: a cross-sectional study

“…The real prevalence of GDM is not known but varies from one geographic region to another. Secondly, the diagnostic criteria used by most studies are not similar [21, 30]. However, the high prevalence of GDM in our study may be attributed to the fact that the population under study falls within the high-risk group for diabetes mellitus (African).…”