Interventions for emergency contraception

Does Levonorgestrel Emergency Contraceptive have a Post-Fertilization Effect? A Review of its Mechanism of Action

“…Reduced progesterone levels, shortened luteal phases, blunted LH levels, and impaired luteal phase endometrial expression of progesteronedependent glycodelin-A, were prominent findings of this serial research (Durand et al 2005(Durand et al , 2010(Durand et al , 2001. Three final studies suggest that LNG-EC alters luteal function with respect to shortened luteal phase and increased vaginal bleeding (Cheng et al 2008;Raymond et al 2006;Gainer et al 2006).…”

Does Levonorgestrel Emergency Contraceptive have a Post-Fertilization Effect? A Review of its Mechanism of Action

“…Reduced progesterone levels, shortened luteal phases, blunted LH levels, and impaired luteal phase endometrial expression of progesteronedependent glycodelin-A, were prominent findings of this serial research (Durand et al 2005(Durand et al , 2010(Durand et al , 2001. Three final studies suggest that LNG-EC alters luteal function with respect to shortened luteal phase and increased vaginal bleeding (Cheng et al 2008;Raymond et al 2006;Gainer et al 2006).…”

Emergency contraception

“…UPA-EC can be used more than once in a menstrual cycle. Research indicates that UPA-EC is better than LNG-EC at preventing pregnancy (Cheng et al., 2012). UPA-EC may therefore be the most suitable oral emergency contraceptive, particularly if sex has taken place in the 6 days preceding ovulation.…”

“…A double 3 mg dose should be given to women who are on enzyme-inducing medications or are overweight (body mass index (BMI) greater than 26 kg/m 2 or weight greater than 70 kg) (FSRH, 2017a). Side effects include menstrual irregularity (Cheng et al., 2012). If vomiting occurs within 3 hours of taking LNG-EC, a repeat dose should be given (Electronic Medicines Compendium, 2017b).…”

Current controversies with oral emergency contraception

“…Follicular development and ovulation are only postponed after intake of EC, so women are at risk of becoming pregnant if further acts of UPSI take place in the same cycle; 5 such risk has been reported as three-to four-fold compared with no further UPSI. 1,49 Based on the half-life of LNG and UPA, repeat use of EC is recommended in the case of further UPSI beyond 24 hours from the last EC use. 66 A study of women taking pericoital LNG-EC repeatedly, i.e.…”

Does Levonorgestrel Emergency Contraceptive have a Post-Fertilization Effect? A Review of its Mechanism of Action

“…Reduced progesterone levels, shortened luteal phases, blunted LH levels, and impaired luteal phase endometrial expression of progesteronedependent glycodelin-A, were prominent findings of this serial research (Durand et al 2005(Durand et al , 2010(Durand et al , 2001. Three final studies suggest that LNG-EC alters luteal function with respect to shortened luteal phase and increased vaginal bleeding (Cheng et al 2008;Raymond et al 2006;Gainer et al 2006).…”

Emergency contraception

“…UPA-EC can be used more than once in a menstrual cycle. Research indicates that UPA-EC is better than LNG-EC at preventing pregnancy (Cheng et al., 2012). UPA-EC may therefore be the most suitable oral emergency contraceptive, particularly if sex has taken place in the 6 days preceding ovulation.…”

“…A double 3 mg dose should be given to women who are on enzyme-inducing medications or are overweight (body mass index (BMI) greater than 26 kg/m 2 or weight greater than 70 kg) (FSRH, 2017a). Side effects include menstrual irregularity (Cheng et al., 2012). If vomiting occurs within 3 hours of taking LNG-EC, a repeat dose should be given (Electronic Medicines Compendium, 2017b).…”

Current controversies with oral emergency contraception

“…Follicular development and ovulation are only postponed after intake of EC, so women are at risk of becoming pregnant if further acts of UPSI take place in the same cycle; 5 such risk has been reported as three-to four-fold compared with no further UPSI. 1,49 Based on the half-life of LNG and UPA, repeat use of EC is recommended in the case of further UPSI beyond 24 hours from the last EC use. 66 A study of women taking pericoital LNG-EC repeatedly, i.e.…”

Does Levonorgestrel Emergency Contraceptive have a Post-Fertilization Effect? A Review of its Mechanism of Action

“…Reduced progesterone levels, shortened luteal phases, blunted LH levels, and impaired luteal phase endometrial expression of progesteronedependent glycodelin-A, were prominent findings of this serial research (Durand et al 2005(Durand et al , 2010(Durand et al , 2001. Three final studies suggest that LNG-EC alters luteal function with respect to shortened luteal phase and increased vaginal bleeding (Cheng et al 2008;Raymond et al 2006;Gainer et al 2006).…”

Emergency contraception

“…UPA-EC can be used more than once in a menstrual cycle. Research indicates that UPA-EC is better than LNG-EC at preventing pregnancy (Cheng et al., 2012). UPA-EC may therefore be the most suitable oral emergency contraceptive, particularly if sex has taken place in the 6 days preceding ovulation.…”

“…A double 3 mg dose should be given to women who are on enzyme-inducing medications or are overweight (body mass index (BMI) greater than 26 kg/m 2 or weight greater than 70 kg) (FSRH, 2017a). Side effects include menstrual irregularity (Cheng et al., 2012). If vomiting occurs within 3 hours of taking LNG-EC, a repeat dose should be given (Electronic Medicines Compendium, 2017b).…”

Current controversies with oral emergency contraception

“…Follicular development and ovulation are only postponed after intake of EC, so women are at risk of becoming pregnant if further acts of UPSI take place in the same cycle; 5 such risk has been reported as three-to four-fold compared with no further UPSI. 1,49 Based on the half-life of LNG and UPA, repeat use of EC is recommended in the case of further UPSI beyond 24 hours from the last EC use. 66 A study of women taking pericoital LNG-EC repeatedly, i.e.…”