Interplay between antioxidants in response to photooxidative stress in Arabidopsis

Kumar, Aditya; Prasad, Ankush; Sedlářová, Michaela; Ksas, Brigitte; Havaux, Michel; Pospı́šil, Pavel

doi:10.1016/j.freeradbiomed.2020.08.027

Cited by 23 publications

(14 citation statements)

References 65 publications

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“…At the highest stringency network (LS ≥ 7), there were 10 edges, with three from glutathione reductase connecting to FRED2, ABC1K3 and ABC1K6. This supports the concept that PGs are part of the redox and antioxidative network, likely able to accept and donate electron through the pool of PQ and other isoprenoidsfor more discussion see (Havaux, 2020) (Pralon et al, 2020;Pralon et al, 2019) (van Wijk andKessler, 2017) (Kumar et al, 2020).…”

Section: Vitamin Biosynthesis (Bin 18) Five Proteins Involved In Vitasupporting

confidence: 71%

Tissue-type specific accumulation of the plastoglobular proteome, transcriptional networks and plastoglobular functions

Michel

Ponnala²,

Wijk

2021

Preprint

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Plastoglobules (PGs) are dynamic protein-lipid micro-compartments in plastids enriched for isoprenoid-derived metabolites. Chloroplast PGs support formation, remodeling and controlled dismantling of thylakoids during developmental transitions and environmental responses. However, the specific molecular functions of most PG proteins are still poorly understood. This study harnesses recent co-mRNA expression from ATTEDII using combined microarray and RNAseq information on an updated inventory of 34 PG proteins, as well as proteomics data across 30 Arabidopsis tissue types from ATHENA. Hierarchical clustering based on relative abundance for the PG proteins across non-photosynthetic and photosynthetic tissue types showed their coordinated protein accumulation across Arabidopsis parts, tissue types, development and senescence. We generated multiple mRNA-based networks by applying different coefficient thresholds; functional enrichment was determined for each network and PG gene. Combined analysis of these stringency networks identified a central hub and four peripheral modules. Enrichment of specific nuclear transcription factors (e.g. Golden2-like) and support for cross-talk between PGs and the plastid gene expression was observed, and specific ABC1 kinases seem part of a light signaling network. Examples of other specific findings are that FBN7b is involved with upstream steps of tetrapyrrole biosynthesis and that ABC1K9 is involved in starch metabolism.

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Section: Vitamin Biosynthesis (Bin 18) Five Proteins Involved In Vitasupporting

confidence: 71%

Tissue-type specific accumulation of the plastoglobular proteome, transcriptional networks and plastoglobular functions

Michel

Ponnala²,

Wijk

2021

Preprint

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“…The more enhanced increase in Asc and total thiol content, as well as in superoxide dismutase and APX activity, was observed in C. reinhardtii grown in the presence of toxic concentrations of heavy metal ions and an inhibitor of HPPD when compared to the heavy metal treated algae in the absence of inhibitor of Toc and PQH 2 synthesis [55]. Deficiency of Toc in Arabidopsis results in accumulation of carotenoid zeaxanthin and vice versa [90,93]. Double Arabidopsis mutant vte1npq1, lacking both Toc and zeaxanthin, displays strong photosensitivity and 1 O 2 -mediated lipid peroxidation under high light conditions [90].…”

Section: Antioxidant Function Of Prenyllipidsmentioning

confidence: 99%

“…•− , able to initiate radical-mediated lipid peroxidation [38]. Plants have evolved various strategies to protect themselves from excessive light, includingsynthesis of low-molecularweight antioxidants, and production of antioxidant enzymes is one of them [41,93].…”

Section: Role Of Prenyllipid Antioxidants In Abiotic Stress Responsementioning

confidence: 99%

Antioxidant and Signaling Role of Plastid-Derived Isoprenoid Quinones and Chromanols

Nowicka

Trela-Makowej

Latowski

et al. 2021

IJMS

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Plant prenyllipids, especially isoprenoid chromanols and quinols, are very efficient low-molecular-weight lipophilic antioxidants, protecting membranes and storage lipids from reactive oxygen species (ROS). ROS are byproducts of aerobic metabolism that can damage cell components, they are also known to play a role in signaling. Plants are particularly prone to oxidative damage because oxygenic photosynthesis results in O2 formation in their green tissues. In addition, the photosynthetic electron transfer chain is an important source of ROS. Therefore, chloroplasts are the main site of ROS generation in plant cells during the light reactions of photosynthesis, and plastidic antioxidants are crucial to prevent oxidative stress, which occurs when plants are exposed to various types of stress factors, both biotic and abiotic. The increase in antioxidant content during stress acclimation is a common phenomenon. In the present review, we describe the mechanisms of ROS (singlet oxygen, superoxide, hydrogen peroxide and hydroxyl radical) production in chloroplasts in general and during exposure to abiotic stress factors, such as high light, low temperature, drought and salinity. We highlight the dual role of their presence: negative (i.e., lipid peroxidation, pigment and protein oxidation) and positive (i.e., contribution in redox-based physiological processes). Then we provide a summary of current knowledge concerning plastidic prenyllipid antioxidants belonging to isoprenoid chromanols and quinols, as well as their structure, occurrence, biosynthesis and function both in ROS detoxification and signaling.

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“…Up-regulation of 4-hydroxyphenylpyruvate dioxygenase (AAEL014600) can be related to plastoquinol and vitamin E (tocopherol) synthesis. Both molecules are described in the literature as participants of antioxidant response to different stimuli in organisms (MaitiDutta et al, 2020;Nowicka et al, 2020), including oxidative stress (Kumar et al, 2020;Minter et al, 2020). In this way, we consider that genes correlated to these pathways were regulated during Wolbachia infection because this microorganism can induce the expression of antioxidant proteins (Brennan et al, 2008).…”

Section: Wolbachia Endosymbiosis Interfere In Glycoconjugates Productmentioning

confidence: 99%

Comprehensive Quantitative Proteome Analysis of Aedes aegypti Identifies Proteins and Pathways Involved in Wolbachia pipientis and Zika Virus Interference Phenomenon

et al. 2021

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Zika virus (ZIKV) is a global public health emergency due to its association with microcephaly, Guillain-Barré syndrome, neuropathy, and myelitis in children and adults. A total of 87 countries have had evidence of autochthonous mosquito-borne transmission of ZIKV, distributed across four continents, and no antivirus therapy or vaccines are available. Therefore, several strategies have been developed to target the main mosquito vector, Aedes aegypti, to reduce the burden of different arboviruses. Among such strategies, the use of the maternally-inherited endosymbiont Wolbachia pipientis has been applied successfully to reduce virus susceptibility and decrease transmission. However, the mechanisms by which Wolbachia orchestrate resistance to ZIKV infection remain to be elucidated. In this study, we apply isobaric labeling quantitative mass spectrometry (MS)-based proteomics to quantify proteins and identify pathways altered during ZIKV infection; Wolbachia infection; co-infection with Wolbachia/ZIKV in the A. aegypti heads and salivary glands. We show that Wolbachia regulates proteins involved in reactive oxygen species production, regulates humoral immune response, and antioxidant production. The reduction of ZIKV polyprotein in the presence of Wolbachia in mosquitoes was determined by MS and corroborates the idea that Wolbachia helps to block ZIKV infections in A. aegypti. The present study offers a rich resource of data that may help to elucidate mechanisms by which Wolbachia orchestrate resistance to ZIKV infection in A. aegypti, and represents a step further on the development of new targeted methods to detect and quantify ZIKV and Wolbachia directly in complex tissues.

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Interplay between antioxidants in response to photooxidative stress in Arabidopsis

Cited by 23 publications

References 65 publications

Tissue-type specific accumulation of the plastoglobular proteome, transcriptional networks and plastoglobular functions

Tissue-type specific accumulation of the plastoglobular proteome, transcriptional networks and plastoglobular functions

Antioxidant and Signaling Role of Plastid-Derived Isoprenoid Quinones and Chromanols

Comprehensive Quantitative Proteome Analysis of Aedes aegypti Identifies Proteins and Pathways Involved in Wolbachia pipientis and Zika Virus Interference Phenomenon

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