Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis

McKinsey, David S.; McKinsey, Joel P.; Northcutt, Noelle; Sarria, Juan C.

doi:10.1016/j.diagmicrobio.2008.09.008

Cited by 15 publications

(14 citation statements)

References 16 publications

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“…We found 1159 studies and included 108 manuscripts published between 1962 and 2022, totaling 298 patients 7–10,12–115 . We excluded 38 articles that could not be retrieved.…”

Section: Resultsmentioning

confidence: 99%

Clinical, radiological and laboratory characteristics of central nervous system histoplasmosis: A systematic review of a severe disease

Oliveira

Kruschewsky

Sekiguchi

et al. 2023

Mycoses

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Background:The knowledge of central nervous system (CNS) histoplasmosis is limited to case reports and series.Objectives: Our objective was to synthesise clinical, radiological and laboratory characteristics of CNS histoplasmosis to improve our understanding of this rare disease. Methods:We performed a systematic review using Pubmed/MEDLINE, Embase and LILACS databases accessed on March 2023 without publication date restrictions.Inclusion criteria comprised: (1) histopathological, microbiological, antigen or serological evidence of histoplasmosis; (2) CNS involvement based on cerebrospinal fluid pleocytosis or neuroimaging abnormalities. We classified the certainty of the diagnosis in proven (CNS microbiological and histopathological confirmation), probable (CNS serological and antigen confirmation) or possible (non-CNS evidence of histoplasmosis). Metaproportion was used to provide a summary measure with 95% confidence intervals for the clinical, radiological and laboratory characteristics. Chi-squared test was used to compare mortality between pairs of antifungal drugs. Results:We included 108 studies with 298 patients. The median age was 31 years, predominantly male, and only 23% were immunocompromised (134/276, 95%CI: 3-71), mainly due to HIV infection. The most common CNS symptom was headache (130/236, 55%, 95%CI: 49-61), with a duration predominantly of weeks or months.Radiological presentation included histoplasmoma (79/185, 34%, 95%CI: 14-61), meningitis (29/185, 14%, 95%CI: 7-25), hydrocephalus (41/185, 37%, 95%CI: 7-83) and vasculitis (18/185, 6%, 95%CI: 1-22). There were 124 proven cases, 112 probable cases and 40 possible cases. The majority of patients presented positive results in CNS pathology (90%), serology (CSF: 72%; serum: 70%) or CSF antigen (74%). Mortality was high (28%, 56/198), but lower in patients who used liposomal amphotericin B and itraconazole. Relapse occurred in 13% (23/179), particularly in HIV patients, but less frequently in patients who used itraconazole. Conclusion:Central nervous system histoplasmosis usually presents subacute-tochronic symptoms in young adults. Neuroimaging patterns included not only focal lesions but also hydrocephalus, meningitis and vasculitis. Positive results were

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“…We found 1159 studies and included 108 manuscripts published between 1962 and 2022, totaling 298 patients 7–10,12–115 . We excluded 38 articles that could not be retrieved.…”

Section: Resultsmentioning

confidence: 99%

Clinical, radiological and laboratory characteristics of central nervous system histoplasmosis: A systematic review of a severe disease

Oliveira

Kruschewsky

Sekiguchi

et al. 2023

Mycoses

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“…In reality, a growing number of analysts have publicly stated their support for mainstream investment strategies that incorporate ESG information. Numerous surveys demonstrating the financial community's understanding and recognition of those extra-financial components support this (McKinsey, 2009). Following that, many academics investigated the association between ESG and the maximization of shareholder value.…”

Section: Literature Reviewmentioning

confidence: 94%

The Effects of ESG issues on investment decision through corporate reputation: Individual investors’ perspective

Rounok

Qian²,

Alam³

2023

IJRBS

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Whether investors take into account a company's environmental, social, and governance (ESG) issues when making investment decisions (ID), how they interpret corporate reputation (CR) as a result of ESG issues, and whether CR mediates the relationship between ESG issues and ID are the goals of this study. The theory of planned behavior (TPB) and the signaling theory are the bases of the framework. The study was based on a questionnaire survey that received 599 responses from active retail investors in two Bangladeshi cities, Dhaka and Chattagram. The PLS path modeling method was used to analyze the data and test the hypothesis. The empirical findings reveal that corporate ESG issues considerably impact ID and that CR mediates this relationship. This study contributes to behavioral finance by offering empirical proof of the relationship between company ESG issues and investment decisions. By examining the indirect effects of ESG issues on ID via CR, this study contributes to the body of knowledge. It is therefore advised that strategic managers be required to use ESG practices as it builds reputation. At the same time, the government should create public policies, orders, and rules for upholding the ESG issues that contribute to the sustainable development of the capital market and the economy.

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“…A monoclonal antibody-based antigen test using analyte-specific reagents (ASR), offered for investigational use only, exhibited 64 % sensitivity [20]. Clinical experience with these assays in clinical practice has not been established, but false results have been reported [21,22]. An assay developed at the Centers for Disease Control and Prevention (CDC) [23] exhibited 81 % sensitivity and 95 % specificity for the diagnosis of PDH in AIDS patients from Guatemala [24].…”

Section: Antigen Detectionmentioning

confidence: 99%

Approach to the Diagnosis of Histoplasmosis, Blastomycosis and Coccidioidomycosis

Wheat¹,

Knox

Hage

2014

Curr Treat Options Infect Dis

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Interlaboratory discrepancy of antigenuria results in 2 patients with AIDS and histoplasmosis

Cited by 15 publications

References 16 publications

Clinical, radiological and laboratory characteristics of central nervous system histoplasmosis: A systematic review of a severe disease

Clinical, radiological and laboratory characteristics of central nervous system histoplasmosis: A systematic review of a severe disease

The Effects of ESG issues on investment decision through corporate reputation: Individual investors’ perspective

Approach to the Diagnosis of Histoplasmosis, Blastomycosis and Coccidioidomycosis

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