2007
DOI: 10.1590/s0100-40422007000300032
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Abstract: Recebido em 6/4/06; aceito em 3/7/06; publicado na web em 7/2/07 ENDOCRINE DISRUPTORS IN THE ENVIRONMENT. Although the hypothesis that environmental chemicals may exhibit endocrine disrupting effects is not new, the issue has been a growing level of concern due to reports of increased incidences of endocrine-related disease in humans, including declining male fertility, and more significantly, to adverse physiological effects observed in wildlife where cause and effect relationships are more evident. The list … Show more

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Cited by 106 publications
(173 citation statements)
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References 30 publications
(173 reference statements)
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“…A volatilidade de uma substancia nos corpos d'água é determinada pela Constante de Henry, porém, dentre os contaminantes emergentes aquáticos abordados neste trabalho, poucos compostos apresentam volatilidade suficiente para que a transferência da fase aquosa para a atmosférica seja um sumidouro efetivo. 82 Para fármacos, hormônios, drogas de abuso e compostos presentes em produtos de higiene pessoal e doméstico, pode-se prever como principal fonte de contaminação os efluentes das ETE. No entanto, o Censo 2010 do Instituto Brasileiro de Geografia e Estatística (IBGE) indicou que apenas 32,9% da população brasileira possui rede coletora de esgoto e apenas parte deste esgoto coletado recebe algum tipo de tratamento antes de ser lançado aos corpos d'água.…”
Section: Fontes E Destino No Ambienteunclassified
“…A volatilidade de uma substancia nos corpos d'água é determinada pela Constante de Henry, porém, dentre os contaminantes emergentes aquáticos abordados neste trabalho, poucos compostos apresentam volatilidade suficiente para que a transferência da fase aquosa para a atmosférica seja um sumidouro efetivo. 82 Para fármacos, hormônios, drogas de abuso e compostos presentes em produtos de higiene pessoal e doméstico, pode-se prever como principal fonte de contaminação os efluentes das ETE. No entanto, o Censo 2010 do Instituto Brasileiro de Geografia e Estatística (IBGE) indicou que apenas 32,9% da população brasileira possui rede coletora de esgoto e apenas parte deste esgoto coletado recebe algum tipo de tratamento antes de ser lançado aos corpos d'água.…”
Section: Fontes E Destino No Ambienteunclassified
“…5 Many of these substances are of great scientific interest due to their ability to interfere with the endocrine system of humans and other animals, as well as their offspring, blocking, mimicking, stimulating and/or inhibiting the production of natural hormones. 4,6,7 These natural or synthetic contaminants are known as endocrine disruptors (EDs) and have been one of the most relevant topics in environmental chemistry in terms of water quality. 2,4,6,7 Dexamethasone, 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, represented by DMZ (Figure 1), is an important catabolic steroid that has a 40-fold greater potency than natural glucocorticoids, such as cortisol and corticosterone, with strong anti-inflammatory and immunosuppressive action.…”
Section: Introductionmentioning
confidence: 99%
“…4,6,7 These natural or synthetic contaminants are known as endocrine disruptors (EDs) and have been one of the most relevant topics in environmental chemistry in terms of water quality. 2,4,6,7 Dexamethasone, 9-fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, represented by DMZ (Figure 1), is an important catabolic steroid that has a 40-fold greater potency than natural glucocorticoids, such as cortisol and corticosterone, with strong anti-inflammatory and immunosuppressive action. 8 Despite its usefulness in the human and veterinary medicine, special care has been dedicated to this drug due to its characteristics as an endocrine disruptor.…”
Section: Introductionmentioning
confidence: 99%
“…This contamination causes serious public health problems and negative impacts on aquatic fauna and flora, besides inducing ecosystem imbalance (Pratt et al, 2008). Several substances have the characteristic of affecting the animals' endocrine system (Bila and Dezotti, 2007), and these endocrine disrupting substances have two classifications: (a) natural, produced by plants and animals (phytoestrogens and estrogens); or (b) synthetic, man-made substances used in the manufacture of oral contraceptives, in hormone replacement, as a feed additive in the diet of several animals (Ghiselli and Jardim, 2007), for use in industry and agriculture, socalled xenoestrogens (Behera et al, 2011). Some examples of synthetic substances are alkylphenols, pesticides, phthalates, polychlorinated biphenyls, bisphenol A and drugs (Table 1).…”
Section: Endocrine Disruptors In the Aquatic Systemmentioning
confidence: 99%