Intercorrelation between Interfacial Behavior of Water and Biocompatibility

PEG functionalization effect of silicate-containing hydroxyapatite particles on effective collagen fibrillation with hydration layer state change

“…When there are no other molecules, a strong hydrogen bond network is formed inside the water cluster. 97 Then, the other water molecules are moved to the Col fibril surfaces as the free water states. Accordingly, the intermediate water molecules of Col are changed to free water in the surrounding environment.…”