Purpose of the review
Pathogens of different taxa, from prions to protozoa, target cellular cholesterol metabolism to advance own development and to impair host immune responses, but also causing metabolic complications, e.g. atherosclerosis. This review describes recent findings of how pathogens do it.
A common theme in interaction between pathogens and host cholesterol metabolism is pathogens targeting lipid rafts of the host plasma membrane. Many intracellular pathogens use rafts as an e…
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