“…Researchers adopting these methods are clear on the importance and utility of the data generated (e.g., Johnson et al, 2019), but often face a difficult decision during the early stages of project design. They must typically choose between the use of a universal probe set (e.g., Buddenhagen et al, 2016;Johnson et al, 2019) developed to work across larger taxonomic scales (e.g., the angiosperms), or a narrower lineage-specific probe set designed for the group of interest (e.g., Mandel et al, 2014;Weitemier et al, 2014;Vatanparast et al, 2018;Gardiner et al, 2019;Koenen et al, 2020). When considering target enrichment options, the core exons of universal probe sets are perhaps viewed as best suited for higher-level phylogenetic problems, where their conserved nature tends to have greatest utility (but see Mitchell et al, 2017;Wanke et al, 2017).…”