In this study, to improve the accuracy of path tracking in intelligent vehicles, we propose an intelligent vehicle path-tracking control method based on improved model predictive control (MPC) combined with hybrid proportional-integral-derivative (PID) control theory. In the lateral control, a constraint on the side deflection of the front wheel is added based on traditional MPC and a relaxation factor is introduced to improve the stability of vehicle control for the driving stability. In longitudinal control, a hybrid PID controller is designed for different road conditions to improve the accuracy of control of vehicle speed. We present the results of a co-simulation using CarSim and MATLAB/Simulink and a test with a sample vehicle, which show that the proposed path tracking controller can greatly improve the path tracking accuracy and stability of an intelligent vehicle. The model-based prediction, rolling optimization solution, feedback control, and the addition of a constraint on the side deflection of the front wheel as well as a relaxation factor can ensure the lateral driving stability of an intelligent vehicle. The proposed approach achieved a lateral error of less than 1%, and the yaw angle was controlled within 4°. The longitudinal speed control based on hybrid PID controller can improve the response speed of the system and meet the real-time requirements of vehicle driving.