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Cited by 63 publications
(49 citation statements)
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References 15 publications
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“…Zinc is known to be insulinomimetic [10] and now a number of experiments have added new information and improved our knowledge. Zinc is co-secreted with insulin and other granule substances.…”
Section: Zinc and Cells Of The Endocrine Pancreasmentioning
confidence: 99%
“…Zinc is known to be insulinomimetic [10] and now a number of experiments have added new information and improved our knowledge. Zinc is co-secreted with insulin and other granule substances.…”
Section: Zinc and Cells Of The Endocrine Pancreasmentioning
confidence: 99%
“…1) We reported that Zn(II) complexes with nicotinamide, maltol, amino acids, picolinic acid, picolinamide, and their derivatives have high insulinomimetic activities in in vitro and in vivo studies. [2][3][4][5][6][7] However, these complexes were effective in showing the lowering effect of blood glucose by daily intraperitonial injections to type 2 diabetes mellitus. When aiming at the clinical use of the complexes, it is essentially important to find complexes that are effective on oral administration.…”
mentioning
confidence: 99%
“…18,19) The inhibitory effect of Zn(car) 2 Cl 2 was compared with those of VOSO 4 and ZnSO 4 as positive controls (Fig. 2).…”
mentioning
confidence: 99%
“…[1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17] However, that method has the disadvantages of increased costs of Zn(II) complexes due to the alkali and large quantity of organic solvents required, along with the undesirable eŠects on the environment and human health alkali used. This paper reports a new method to obtain Zn(II) complexes at high yields (more than 90%) by direct mixing of solid ligands and solid Zn(OH) 2 or ZnO with or without the addition of a minimum amount of water without the use of alkali and organic solvents.…”
Section: Introductionmentioning
confidence: 99%