2010
DOI: 10.1186/1758-5996-2-11 View full text |Buy / Rent full text
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Abstract: BackgroundInsulin-resistance is associated with cardiovascular disease but it is not used as a marker for disease in clinical practice.AimsTo study the association between the homeostatic model assessment (HOMA-IR) and triglyceride/HDLc ratio (TG/HDLc) with the presence of coronary artery disease in patients submitted to cardiac catheterization.MethodsIn a cross-sectional study, 131 patients (57.0 ± 10 years-old, 51.5% men) underwent clinical, laboratory and angiographic evaluation and were classified as No CA… Show more

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“…There was no significant difference of diabetes mellitus between the groups (p=0.418). This result was correlated with the study of Bertoluci et al 28 that 48.6% of their CAD patients were diabetics.…”
Section: Materials and Methodsupporting
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“…There was no significant difference of diabetes mellitus between the groups (p=0.418). This result was correlated with the study of Bertoluci et al 28 that 48.6% of their CAD patients were diabetics.…”
Section: Materials and Methodsupporting
“…In one study, decreased insulin sensitivity was associated with increased incidence of myocardial infarction and death, even after adjusting cardiovascular risk for smoking and low physical activity. Bertoluci et al also indicated that increased HOMA of insulin resistance was positively associated with angiographic coronary artery disease [30] . As a result, decreased omentin-1 levels may contribute to development of CAD by modulating insulin action.…”
Section: Discussionmentioning
“…HOMA-IR, TG, and leptin are log transformed * Factor loadings C |0.40| higher AUCs for detecting high LDL-C levels in a model which comprises both TG and HDL-C levels. However, TG/HDL-C ratio is suggested to be a reliable index in predicting insulin resistance [22] and coronary artery disease [23]. In a multivariable-adjusted logistic regression analysis, on the contrary to HDL-C, TG/HDL-C ratio was revealed to be associated with number of MetS components and HOMA-IR by sex strata in both participants with and without MetS [24].…”
Section: Discussionmentioning