Insulin Quantification in Patients With Seborrheic Dermatitis

Dowlati, Bijan; Firooz, Alireza; Khamesipour, Ali; Lotfi, Mehdi; Stuart, Charles Alexander; Smith, Edgar B.; Larijani, Bagher; Dowlati, Yahya

doi:10.1001/archderm.134.8.1043

Cited by 11 publications

(8 citation statements)

References 2 publications

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“…As opposed to acne vulgaris, seborrheic eczema does not show any direct correlation to increased insulin and IGF‐1 levels in the serum although sebum production is also increased [106].…”

Section: Seborrheic Eczemamentioning

confidence: 99%

The impact of clinical nutrition on inflammatory skin diseases

Guertler

Schmitt

2022

J Deutsche Derma Gesell

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The influence of nutrition on the pathophysiology and clinical severity of inflammatory facial dermatoses such as acne, rosacea, seborrheic dermatitis, and perioral dermatitis has been controversially discussed for years. As part of a modern treatment approach, clinicians should provide patients with information on how their choice of diet might impact their dermatologic diagnosis and could potentially enhance therapeutic outcome. Recently, the concept of a gut-skin axis has gained momentum in the understanding of inflammatory dermatoses, with nutrition considered a contributing factor in this context. For example, gastrointestinal symptoms in rosacea patients may indicate a dysbiosis of the gut microbiome, treatment of which may also improve severity of the skin disease. New research efforts were recently made for acne patients addressing the clinical effects of omega-3 fatty acids and probiotics. In contrast, due to the limited data available, no comparable specific dietary recommendations can yet be made for seborrheic or perioral dermatitis. However, there are promising signs that clinical nutrition and dermatology will be more extensively interlinked in the future, both clinically and scientifically.

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“…As opposed to acne vulgaris, seborrheic eczema does not show any direct correlation to increased insulin and IGF‐1 levels in the serum although sebum production is also increased [106].…”

Section: Seborrheic Eczemamentioning

confidence: 99%

The impact of clinical nutrition on inflammatory skin diseases

Guertler

Schmitt

2022

J Deutsche Derma Gesell

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“…However, other factors may be relevant. For example, Malassezia furfur infection is necessary for seborrhoeic dermatitis to occur 119 . Finger pebbles, a papular thickening over the fingers, occurs in both diabetes and obesity 120 …”

Section: Obesity and Other Common Skin Conditionsmentioning

confidence: 99%

Obesity and the skin

Shipman

Millington

2011

British Journal of Dermatology

132

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Obesity is a serious global health problem, perhaps the biggest public health issue of our times. Excess body weight may be a factor in carcinogenesis in general, as well as contributing to the pathogenesis of metabolic, cardiovascular and musculoskeletal disorders. Obesity also has many cutaneous features, which form the basis for this review article. Many of these clinical entities are common to the majority of obese patients, e.g. striae distensae, plantar hyperkeratosis and an increased risk of skin infections. However, it may also be associated with poor wound healing, malignant melanoma and an increased risk of inflammatory dermatoses, such as psoriasis, as well as some rarer disorders. Therapeutic interventions for obesity, whether over-the-counter, prescription medicines or surgical interventions, are increasingly commonplace. All of these treatment modalities potentially have dermatological side-effects too.

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“…The mechanisms involved in this association are yet unknown. Obesity is related to insulin resistance, but one study failed to associate high insulin levels with occurrence of SD 16 . On the other hand, obesity may lead to hyperandrogenism and elevation of testosterone levels, and the latter is potentially responsible for increased seborrhea 17,18 .…”

Section: Commentmentioning

confidence: 99%