Insuffisance rénale aiguë secondaire à la povidone iodée

Béji, S.; Kâaroud, H.; Moussa, F. Ben; Abderrahim, E.; Zghidi, Souheil; Hamida, F. Ben; Maı̈z, H. Ben; Kheder, A.

doi:10.1016/s0755-4982(06)74522-5

Cited by 11 publications

(9 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We report a case of a young adult woman who developed PI-induced AKI, after a diagnostic hysteroscopy and laparoscopy procedure in terms of infertility evaluation. To our knowledge, this is the first case of PIinduced AKI in the Republic of Cyprus, and one of the few [8][9][10] in the published literature associated with a gynecology procedure.…”

Section: Introductionmentioning

confidence: 80%

Povidone-Iodine-Induced Acute Kidney Injury in a 23-Year-Old Woman: The First Clinical Case Report From the Republic of Cyprus

Papadopoulos¹,

Iordanou²,

Georgiou³

et al. 2022

Cureus

View full text Add to dashboard Cite

Povidone-iodine (PI) is considered a generally safe broad-spectrum, antiseptic substance, which is widely used in healthcare services, mostly for burn patients, in wound treatment, surgical wound irrigation, as well as for a few gynecological indications. Although it is safe, its use on mucosa can cause toxicity due to iodine absorption and the high concentration in the serum. PI toxicity is absorption depended and has been associated with severe adverse events including acute kidney injury (AKI). To our knowledge, there are only three cases of PI-induced AKI after uterine instillation in the published literature. We report a case of severe PI-induced AKI that occurred in a 23-year-old female due to iodine systemic absorption immediately post uterine instillation, in terms of infertility evaluation.The patient was admitted to the intensive care unit (ICU), supported with mechanical ventilation and treated with renal replacement therapy (RRT). Renal function and urine output improved and the patient was discharged from ICU.Severe adverse events may be linked to internal use, therefore, PI on mucosa should be used with extreme caution. Clinicians should be aware of iodine intoxication and possible AKI.

show abstract

Section: Introductionmentioning

confidence: 80%

Povidone-Iodine-Induced Acute Kidney Injury in a 23-Year-Old Woman: The First Clinical Case Report From the Republic of Cyprus

Papadopoulos¹,

Iordanou²,

Georgiou³

et al. 2022

Cureus

View full text Add to dashboard Cite

show abstract

“…30,31 Iodine analogues also possess good antimicrobial 31 but have been reported to be toxic in certain situations. [31][32][33][34][35][36] There is also increasing concern about the use of chlorhexidine preparations in wound dressings due to the development of antimicrobial resistance and toxicity. 37,38 A Cochrane Collaboration report stated that honey may be superior to some conventional dressing materials, 39 but there is considerable uncertainty about the replicability and applicability of this evidence.…”

Section: Discussionmentioning

confidence: 99%

A multi-centre clinical evaluation of reactive oxygen topical wound gel in 114 wounds

et al. 2016

View full text Add to dashboard Cite

show abstract

“…However, on review of the PubMed database, we found other cases of CI-AKI in patients who did not receive any intravascular injection of CM. In fact, these patients either underwent diagnostic hepatobiliary [3–8] and gynaecological [9–11] procedures with iodinated CM, or had topical treatments using iodinated antimicrobials [12–18]. Some clinical data of the 33 cases reported in the literature, including the one here presented, are summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

“…Accordingly, this extremely hazardous workup examination has been replaced by more accurate and safe diagnostic tests [19]. Similarly, because of several reported cases of systemic toxicity, it is clear that the use of povidone-iodine as CM for gynaecological diagnostic procedures should also be avoided [9, 11]. …”

Section: Discussionmentioning

confidence: 99%

Contrast-induced acute kidney injury following iodine opacification other than by intravascular injection

Perrin¹,

Hemett²,

Menth³

et al. 2012

Clinical Kidney Journal

View full text Add to dashboard Cite

Contrast-induced acute kidney injury (CI-AKI) classically occurs following the intravascular administration of iodinated contrast medium (CM). However, some cases of iodine-induced nephrotoxicity have been reported in patients who did not receive intravascular CM, as a consequence of iodine absorption through mucosae, burned skin or interstitial tissues. Recently, we observed the first case of CI-AKI occurring after an enteroclysis without any direct intravascular injection of CM. Here, we report this case, and review other clinical situations in which renal toxicity has been reported following the non-intravascular use of iodinated compounds.

show abstract

Insuffisance rénale aiguë secondaire à la povidone iodée

Cited by 11 publications

References 10 publications

Povidone-Iodine-Induced Acute Kidney Injury in a 23-Year-Old Woman: The First Clinical Case Report From the Republic of Cyprus

Povidone-Iodine-Induced Acute Kidney Injury in a 23-Year-Old Woman: The First Clinical Case Report From the Republic of Cyprus

A multi-centre clinical evaluation of reactive oxygen topical wound gel in 114 wounds

Contrast-induced acute kidney injury following iodine opacification other than by intravascular injection

Contact Info

Product

Resources

About