Insomnia symptoms predict both future hypertension and depression

Dong, Yutong; Yang, Frances M.

doi:10.1016/j.ypmed.2019.02.001

Cited by 32 publications

(37 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Older age was identified as a risk factor in five studies [ 2 , 38 , 41 – 43 ] but was not significant in eleven studies [ 18 , 24 , 26 , 27 , 29 , 30 , 35 – 37 , 40 , 44 ]. Additionally, older age was insignificant in both men and women analyzed separately in one study [ 18 ] and increased risk for depression in women, but not in men in another [ 20 ].…”

Section: Resultsmentioning

confidence: 99%

“…Lifestyle factors. Participating in a physical activity was identified as a protective factor by one study of medium quality [30] However, a Finish sample of non-institutionalized seniors did not find a significant difference between the onset of depression in the subgroups disabled-sedentary, disabled-active, and mobile-sedentary as compared to a mobile-active subgroup in multivariate analysis [38]. In another study, some specific forms of physical activity, such as walking habits and moderate physical exercise, yielded insignificant results, however light physical exercise was found to be a protective factor [23].…”

Section: Plos Onementioning

confidence: 99%

See 1 more Smart Citation

Risk factors and protective factors of depression in older people 65+. A systematic review

et al. 2021

View full text Add to dashboard Cite

Objectives Identifying risk factors of depression can provide a better understanding of the disorder in older people. However, to minimize bias due to the influence of confounders and to detect reverse influence, a focus on longitudinal studies using multivariate analysis is required. Design A systematic literature search was conducted by searching the databases MEDLINE, Cochrane, PsycINFO and Web of Science for all relevant articles published from January 2000 to the end of March 2020. The following inclusion criteria were used: prospective design, nationally or regionally representative sample, published in English or German, analyzed risk factors for depression of individuals 65+ identified by multivariate analysis, and provided validity of diagnostic instrument. All results of multivariate analysis were reported and summarized. Results Thirty articles were identified. Heterogeneous results were found for education, female gender, self-rated health, cognitive impairment and older age, although significant in several studies. Findings hinted at a protective quality of physical activity. In terms of physical health, chronic disease and difficulty initiating sleep homogeneously increased risk of depression. Mobility impairment resulted as a risk factor in three studies. IADL impairment and vision impairment were mostly identified as significant risk factors. Alcohol consumption and smoking behavior yielded heterogenous results. Psychosocial factors were assessed similarly in multiple studies and yielded heterogenous results. Limitations Research was limited to articles published in English or German. Length of follow up was not considered for the presentation of results. Adjustments for and inclusion of different variables in the studies may distort results. Conclusion Our findings demonstrate the necessity of refined, more comparable assessment tools for evaluating potential risk factors.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Plos Onementioning

confidence: 99%

Risk factors and protective factors of depression in older people 65+. A systematic review

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Many articles have explored the mechanism of their relationship as well. [ 41 , 42 ] With the increase in the explorations of the intestinal flora in recent years, more evidence indicates that the intestinal flora affects inflammatory compounds as well as emotional state and cognition by participating in short-chain fatty acid (SCFA) metabolism (non-digestible polysaccharides produced by SCFAs during fermentation). Disorders of short-chain fatty acid metabolism are also playing an increasingly important role in depression.…”

Section: Discussionmentioning

confidence: 99%

The effect of acupuncture on depression and its correlation with metabolic alterations

Sun

Yin

et al. 2020

Medicine

View full text Add to dashboard Cite

Background: Electroacupuncture (EA) treatment has antidepressant effect and when patients were treated with EA and antidepressants, the effect could be maintained for a longer time. However, the effect of EA combined with antidepressants based on metabolism is still in the initial observation stage, which requires further research. Methods: A total of 60 patients with moderate depression were assigned into 2 groups at a ratio of 1:1, the EA group (receiving EA and antidepressants) and the control group (taking antidepressants only) in this randomized controlled pilot trial. The EA treatment was performed 3 times a week for 8 consecutive weeks and then follow up for 4 weeks. The patients’ depressive mood was measured by the Hamilton Depression scale (HAMD) at baseline, week 4, week 8 and week 12. Before and after 8-week treatment, morning urine samples from all patients were analyzed by the gas chromatography–mass spectrometry (GC–MS) to find possible metabolic markers of depression and of EA treatment related changes. Results: Compared with the control group, the EA group showed more significant improvements in depressive symptoms measured by HAMD at week 4 (16.89 ± 5.74 vs 25.58 ± 7.03, P < .001), week 8 (9.59 ± 5.13 vs 25.04 ± 7.49, P < .001) and week 12 (11.07 ± 6.85 vs 27.25 ± 7.14, P < .001). The significant differences in urinary specific metabolites before and after EA treatment were malonic acid (fatty acid biosynthesis), cysteine (glutamate metabolism), glutathione (glutamate metabolism), tryptophan (tryptophan metabolism), proline (glutamate metabolism), and N-acetyl-5-hydroxytryptamine. These metabolites are involved in tryptophan metabolism, glutamate metabolism, and fatty acid biosynthesis. Conclusion: EA treatment combined with antidepressants is more effective in improving depressive symptoms than antidepressants alone. EA may treat depression by acting on tryptophan metabolism, glutamate metabolism, and fatty acid biosynthesis. Trial registration: Chinese Clinical Trial Registry: ChiCTR-2000030786.

show abstract

“…It is well established that impaired sleep increases the risk of several health problems of varying severity, for instance all-cause cardiopulmonary mortality, respiratory tract infections, hypertension as well as depression. [15][16][17] Current evidence suggests that sleep disturbances are a risk factor for the onset of NBP, 18 as well as a prognostic factor in subacute or long-lasting pain conditions, 19 20 and for sickness absence. 21 Hypothesising that poor work ability and sleep disturbances are independent risk factors for the development of LNBP, it is possible that having both factors results in a synergistic effect.…”

Section: Introductionmentioning

confidence: 99%

Risk of transition from occasional neck/back pain to long-duration activity limiting neck/back pain: a cohort study on the influence of poor work ability and sleep disturbances in the working population in Stockholm County

et al. 2020

View full text Add to dashboard Cite

ObjectivesThe prevalence of neck/back pain (NBP) is high worldwide. Limited number of studies have investigated workers with occasional NBP regarding the risk of developing long-duration activity limiting NBP (LNBP). The objectives were to assess (1) the effect of poor work ability and sleep disturbances in persons with occasional NBP on the risk of LNBP, and (2) the interaction effect of these exposures.DesignCohort study based on three subsamples from the Stockholm Public Health Cohort.SettingsThe working population in Stockholm County.ParticipantsPersons aged 18–60 years, reporting occasional NBP the past 6 months at baseline year 2010 (n=16 460).MeasuresWork ability was assessed with items from the Work Ability Index, perceived mental and/or physical work ability. Sleep disturbances were self-reported current mild/severe disturbances. The outcome in year 2014 was reporting NBP the previous 6 months, occurring ≥couple of days per week and resulting in decreased work ability/restricted other daily activities. The additive effect of having both poor work ability and sleep disturbances was modelled with a dummy variable, including both exposures. Poisson log-linear regression was used to calculate risk ratios (RRs) and 95% CIs.ResultsAt follow-up, 9% had developed LNBP. Poor work ability and sleep disturbances were independent risk factors for LNBP; adjusted RR 1.7 (95% CI: 1.4 to 2.0) and 1.4 (95% CI: 1.2 to 1.5), respectively. No additive interaction was observed.ConclusionWorkers with occasional NBP who have poor work ability and/or sleep disturbances are at risk of developing LNBP. Having both conditions does not exceed additive risk.

show abstract

Insomnia symptoms predict both future hypertension and depression

Cited by 32 publications

References 40 publications

Risk factors and protective factors of depression in older people 65+. A systematic review

Risk factors and protective factors of depression in older people 65+. A systematic review

The effect of acupuncture on depression and its correlation with metabolic alterations

Risk of transition from occasional neck/back pain to long-duration activity limiting neck/back pain: a cohort study on the influence of poor work ability and sleep disturbances in the working population in Stockholm County

Contact Info

Product

Resources

About