2021
DOI: 10.1016/j.tacc.2020.09.005
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Novel coronavirus spread rapidly around the world infecting millions of people. It was thus declared a pandemic. This new virus damages the lungs. In the most severe cases, it leads to acute respiratory failure that requires intensive care treatment. However, many clinical reports have listed different neurological symptoms, leading to increased interest in the neurological involvement of COVID-19. Various pathophysiological mechanisms have been proposed to explain these neurological aspects. Direct… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

0
18
0
1

Year Published

2021
2021
2023
2023

Publication Types

Select...
9

Relationship

3
6

Authors

Journals

citations
Cited by 26 publications
(19 citation statements)
references
References 91 publications
(108 reference statements)
0
18
0
1
Order By: Relevance
“…The CVH/ICC score was similar at the two time-points (p = 0.48) for the 29 patients with two assessments. (14 [11-25] vs. 11 [7][8][9][10][11][12][13][14][15] mmHg; p = 0.01) were significantly higher among patients with UO than the others.…”
Section: Icc and Cvh Assessmentmentioning
confidence: 95%
See 1 more Smart Citation
“…The CVH/ICC score was similar at the two time-points (p = 0.48) for the 29 patients with two assessments. (14 [11-25] vs. 11 [7][8][9][10][11][12][13][14][15] mmHg; p = 0.01) were significantly higher among patients with UO than the others.…”
Section: Icc and Cvh Assessmentmentioning
confidence: 95%
“…As many COVID-19 patients experience neurological symptoms, such as headache, anosmia, paresthesia, nausea, vomiting, and alteration of consciousness [11], one hypothesis could also be that intracranial compliance (ICC) and cerebrovascular hemodynamics (CVH) are impaired in the early course of the disease, either directly (i.e., encephalitis, brain edema, or focal ischemia) or indirectly (i.e., hypoxic distress, cytokine storm, and endothelial dysfunction) [12,13]. This would be even more frequent in critically ill patients, who often suffer from persistent somnolence, lethargy, and delirium [14,15].…”
Section: Introductionmentioning
confidence: 99%
“…Noteworthy, in COVID-19 patients, the control of breathing is particularly tricky due to the direct involvement of central neural nervous system by SARS-CoV-2 [ 33 , 34 ] and the modifications of angiotensin-mediated sensitivity of the carotid bodies, expressing angiotensin-converting-enzyme 2 receptors [ 35 ]. Thus, in COVID-19 patients, the assessment of respiratory drive and inspiratory efforts are of pivotal importance in understanding the role played by patient-self-induced lung injury (PSILI) on disease progression [ 36 ].…”
Section: Discussionmentioning
confidence: 99%
“…Anosmia and ageusia are also frequent and helpful in the young and women, but not determinant to diagnose COVID-19 infection [ 6 ]. Other neurological symptoms are consciousness alterations, encephalitis, and stroke [ 7 ]. SARS-CoV-2 infection can progress to an acute respiratory distress syndrome needing ICU admission and associated with a high mortality rate [ 8 , 9 , 10 ].…”
Section: Introductionmentioning
confidence: 99%