“…C. elegans assays were first used as a biological model and in environmental and chemical toxicity to obtain data from a whole animal with active digestive, reproductive, sensory, and neuromuscular systems 110 , 111 . Nowadays, this model is used in drug toxicity analysis, such as cisplatin 112 and aesculin, a coumarin compound extracted from TCM Qinpi (Cortex Fraxini) 113 .…”