Insight of Prevalence, Toxin Typing and Antimicrobial Susceptibility of Egyptian Clostridium perfringens Isolates Recovered from Broiler, Layer and Breeder Chicken Flocks

Abstract

Clostridial infection is associated with significant health problems in poultry today, as its enteritis affects intestinal integrity in poultry flocks and may cause considerable losses, which caused by Clostridium perfringens that found all over the world, so fighting this infection is a continuing challenge for the poultry sector. Preventive actions using dedicated products are a valuable solution to maintain healthy gut flora. In this study the prevalence of Clostridium perfringens was detected in different chicken flocks at a rate of 32%. Also, toxin-typing showed presence of cpa, cpb, etx, iap and cpe toxins among the isolates which mainly associated with necrotic enteritis cases. Net-B toxin is a novel toxin that had been recently identified in virulent avian C. perfringens isolates and it presence potentiate the necrotic lesions and destroy the enterocytes. Antimicrobial patterns showed high resistance against most common antibacterial drugs as β-lactams, aminoglycosides, macrolides and tetracyclines. NetB toxin harboring isolates, originating from diseased broiler, layer and breeder chickens showed the lowest minimum inhibitory concentration MICs values for the penicillin from β-lactams and tylvalosin from macrolides.

Subclinical Clostridium Perfringens Infection and Marek’s Disease in Jordanian Broiler Chickens

“…Duo to the subclinical disease, there is chronic damage to the intestinal mucosa of the chickens, which leads to impaired absorption of nutrients, reduced weight gain, and decreased overall performance. As a result of these factors, subclinical NE causes substantial economic losses to the poultry industry (Kaldhusdal et al 2016;Emami and Dalloul 2021;Bastamy et al 2022;He et al 2022). These losses are anticipated to be 2 billion dollars annually (Svobodová et al 2007;Wang et al 2017;Khalique et al 2020).…”

Role of Clostridium Perfringens and Escherichia Coli in the Occurrence of Diarrhea in newborn Rabbits

“…Another most important etiological agent of gastrointestinal infections in rabbits is Enteropathogenic Escherichia coli (EPEC). It causes dehydration, fatigue, and watery diarrhea that may be mucoid or bloody in nature (Swennes et al 2012; Bakry et al 2021;Bastamy et al 2022). This study was planned to investigate the prevalence of E. coli and Clostridium spp. in rabbits suffering from weaning diarrhea, as well as from their environment.…”