Insight into membrane selectivity of linear and branched polyethylenimines and their potential as biocides for advanced wound dressings

Fox, Stephen; Fazil, Mobashar Hussain Urf Turabe; Dhand, Chetna; Mayandi, Venkatesh; Goh, Eunice Tze Leng; Harini, Sriram; Eugene, Christo; Lim, Rayne Rui; Ramakrishna, Seeram; Chaurasia, Shyam S.; Beuerman, Roger W.; Verma, Chandra; Verma, Navin Kumar; Loh, Xian Jun; Lakshminarayanan, Rajamani

doi:10.1016/j.actbio.2016.04.015

Cited by 41 publications

(44 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a result, the pDA-coated electrospun gelatin displayed better aqueous durability and mechanical properties than pristine gelatin nanofibers. We further demonstrated that alkaline exposure did not alter the antimicrobial properties of cationic polymers, antibacterials or antifungal compounds [76,77]. Interestingly, the combined effect of pDA coating and antibacterials/antifungals which interact with the gelatin nanofibers resulted in long-term antimicrobial activity and excellent durability of gelatin nanofibers.…”

Section: Applications Of Pda Coating For Electrospun Polymersmentioning

confidence: 76%

Oxidative Polymerization of Dopamine: A High-Definition Multifunctional Coatings for Electrospun Nanofibers - An Overview

Lakshminarayanan¹,

Srinivasan²,

Sim³

2018

Dopamine - Health and Disease

Self Cite

View full text Add to dashboard Cite

The invention that catecholamines undergo oxidative polymerization under alkaline conditions and form adhesive nanocoatings on wide variety of substrates has ushered their potential utility in engineering and biomedical applications. The oxidative polymerization of catecholamines can be triggered by light, chemical and physical methods, thus representing one of the widely explored surface coating methods. The overall objectives of this chapter are to compile the various methods of accomplishing surface coatings and compare the structural diversity of catecholamines. The progress achieved so far on polydopamine (pDA) coatings on electrospun polymers will be discussed. Finally, we will summarize the research efforts on catecholamine coatings for biomedical applications as well as their potential as a high definition coating method.

show abstract

Section: Applications Of Pda Coating For Electrospun Polymersmentioning

confidence: 76%

Oxidative Polymerization of Dopamine: A High-Definition Multifunctional Coatings for Electrospun Nanofibers - An Overview

Lakshminarayanan¹,

Srinivasan²,

Sim³

2018

Dopamine - Health and Disease

Self Cite

View full text Add to dashboard Cite

show abstract

“…One attractive category of polymers is PEI, one of the polymers with the highest amine content. Linear PEI containing terminal primary amines and secondary amines in the backbone shows potent antimicrobial capability, with MIC being able to be reduced to 31 µg/mL for E. coli and 8 µg/mL for S. aureus , respectively, and lower than the precursor, oligo(2‐oxazoline)s . In comparison, branched PEI, containing primary, secondary, and tertiary amines, showed less antimicrobial activity in vitro when incubation time with bacteria was 24 h; but no significant difference when incubation time was 48 h .…”

Section: Introductionmentioning

confidence: 96%

“…Linear PEI containing terminal primary amines and secondary amines in the backbone shows potent antimicrobial capability, with MIC being able to be reduced to 31 µg/mL for E. coli and 8 µg/mL for S. aureus , respectively, and lower than the precursor, oligo(2‐oxazoline)s . In comparison, branched PEI, containing primary, secondary, and tertiary amines, showed less antimicrobial activity in vitro when incubation time with bacteria was 24 h; but no significant difference when incubation time was 48 h . In addition, the terminal primary amines of branched PEI were conjugated with species containing quaternary amines forming polymers containing secondary, tertiary and quaternary amines with potent antimicrobial activity .…”

Section: Introductionmentioning

confidence: 99%

Developments in antimicrobial polymers

Ren

Cheng

Wang

et al. 2016

J. Polym. Sci. Part A: Polym. Chem.

View full text Add to dashboard Cite

Effective antimicrobial polymers have been attracting more interests because of the low propensity to cause drug‐resistant microorganisms. The recent progresses in antimicrobial polymers are updated according to the action approaches, that is, antimicrobial polymers with free mobility or fixed on surfaces, respectively. Free antimicrobial polymers kill pathogens majorly via electrostatic interaction followed by disruption of the cell membranes; strong antimicrobial activity of primary/secondary amines, new chemical units, and peptides without facial amphiphilicity are highlighted; and the dependences on amphiphilicity, topology, and self‐assembly profiles are summarized. Antimicrobial polymers fixed on surfaces kill pathogens via interaction with the cell membranes of pathogens via electrostatic or hydrophobic interaction; approaches to antimicrobial surfaces based on covalently grafting, anchoring, and bulk‐mixing of polymers are summarized; and new designs of sustainable antimicrobial surfaces and hydrogels are highlighted. Deep biology understanding and development strategies of materials are suggested for the future. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017, 55, 632–639

show abstract

“…Among the major applications of the TiO2 nanoparticles, are the degradation of chlorinated compounds like 2-chlorophenol, 2,4dichlorophenol and 2,4,6-trichlorophenol which are used as intermediates in the making of insecticides, herbicides, preservatives etc., which cause severe environmental pollution due to their mutagenicity and carcinogenicity [6,7]. Nanoparticulate TiO2 as antibacterial coatings and wastewater disinfectants have been reported [8].…”

Section: Introductionmentioning

confidence: 99%

Study on Photo-Catalytic and Antimicrobial Activity of Green Synthesized TiO2 Nanoparticles Coated Vitrified Tiles

Sivaraj¹,

Sudhakar²,

Arivanandhan³

et al. 2019

JNST

View full text Add to dashboard Cite

In the current study, a facile and eco-friendly method has been developed for the synthesis of titanium dioxide nanoparticles from titanium isopropoxide solution using Datura metel (Vellai Umathai) leaves and orange peel extract. Silver nanoparticles (60 nm) and silver nanoplates (130 nm) have been synthesized and characterized using UV-visible spectroscopy, X-ray diffractometer (XRD), atomic force microscopy (AFM) and scanning electron microscopy (SEM). The silver nanoparticles are doped with TiO2 nanoparticles. The photocatalytic activity of Ag nanoparticles and nanoplates doped TiO2 nanoparticles coated on vitrified tiles was investigated, wherein, degradation of methylene blue, rapidly on exposure to sunlight was observed. Analysis of the antimicrobial activity measured using colony forming units showed a 4-log reduction in the growth of the Gram-negative bacteria and a 5-log reduction in the growth of the Gram-positive bacteria.

show abstract

Insight into membrane selectivity of linear and branched polyethylenimines and their potential as biocides for advanced wound dressings

Cited by 41 publications

References 62 publications

Oxidative Polymerization of Dopamine: A High-Definition Multifunctional Coatings for Electrospun Nanofibers - An Overview

Oxidative Polymerization of Dopamine: A High-Definition Multifunctional Coatings for Electrospun Nanofibers - An Overview

Developments in antimicrobial polymers

Study on Photo-Catalytic and Antimicrobial Activity of Green Synthesized TiO2 Nanoparticles Coated Vitrified Tiles

Contact Info

Product

Resources

About