Inside Front Cover: Designed Fabrication of Silica-Based Nanostructured Particle Systems for Nanomedicine Applications (Adv. Funct. Mater. 23/2008)

Recent Progress on Silica Coating of Nanoparticles and Related Nanomaterials

“…[34] Yang et al [35] have successfully prepared highly photostable, fluorescent silica-coated QDs (CdS@SiO 2 and CdTe@SiO 2 ), showing reduced cytotoxicity. The shell thickness could be simply tuned through the amount of TEOS, whereas the number of QD cores was controlled by addition of polyelectrolytes, such as poly(diallyldimethylammonium chloride) (PDDA), in the microemulsions, giving rise to either core-shell or raisin-bun-type structures ( Fig.…”

“…Additionally, this coating should endow the cores with several beneficial properties, such as the possibility of subsequent functionalization and biocompatibility, [8] which allow the use of these nanomaterials to enhance both diagnostic and therapeutic techniques (e.g., magnetic resonance imaging, MRI). [9] A number of reports have been devoted to silica coating of colloidal nanoparticles by aqueous classical methods such as Stöber synthesis, [10,11] use of silane coupling agents, [12] and the sodium silicate water-glass methodology. [13,14] Since this is a rapidly expanding field that is currently undergoing fast development, we intended to review in this progress report a selection of recent work related to various types of silica-coated nanomaterials.…”

Alternating Silica/Polymer Multilayer Hybrid Microspheres Templates for Double-shelled Polymer and Inorganic Hollow Microstructures

“…Furthermore, silica has been approved as safe by the U.S. Food and Drug Adminstration (FDA). Silica-based micro- or nanomaterials with hierarchical structures have been widely investigated to broaden their applications in adsorption and separation, catalysis, sensors and nanomedicine. − For instance, stable Pt/mesoporous silica (Pt@mSiO 2 ) core−shell nanoparticles have been synthesized for high-temperature catalytic reactions . Yolk/SiO 2 shell structures with encapsulated Au and Fe 2 O 3 nanoparticles have been developed .…”

Ratiometric and reusable fluorescent nanoparticles for Zn2+ and H2PO4− detection in aqueous solution and living cells

“…Around this core-shell, some functional molecules can be deposited. 18 Recently, silica nanoparticles have been investigated as the matrix of chemosensors, and most of them are used for the detection of the fluorescence quenching species, such as molecular oxygen 19 and Cu 2+ , 20 Pb 2 + 17 ions. Reports on the elaboration of optical silica nanoparticles chemically bound with fluorophores, especially with the enhancement of the fluorescence intensity for Zn 2+ , are quite scarce.…”